TRANSPOSITIONS # Tp(1;1)7B-7E cytology: Tp(1;1)7B5-C1;7E1-2;9C2-D1. origin: Spontaneous in an outcross of the L strain of Lim, 1979. The L strain has numerous gypsy elements which are mobilized in certain outcrosses (Jack and Judd). references: Lim, 1979, Genetics 93: 681-701. # Tp(1;1)303-1: see In(1)303-1 # Tp(1;1)A101 cytology: Tp(1;1)11A1-2;12E8-9;18B. new order: 1 - 11A1|18B - 12E9|11A2 - 12E8|18B - 20. discoverer: Lefevre. genetics: Lethal at 11A1-2. # Tp(1;1)At: see In(1)At # Tp(1;1)B263-24: see In(1)B263-24 #*Tp(1;1)B263-48: Transposition (1;1) Bar cytology: Tp(1;1)3E2-3;15F9-16A1;20A2-3. new order: 1 - 3E2|16A1 - 20A2|3E3 - 15F9|20A3 - 20F. origin: X ray induced. discoverer: Bishop, 1939. references: Sutton, 1943, Genetics 28: 99. genetics: Male and homozygous female viable. Crossing over in Tp(1;1)B263-48/+ heterozygote yields Dp(1;1)B263-48 (new order: 1 - 3E2|16A1 - 20A2| 3E3 - 20F), which is heterozygous viable and Bar. The complementary deficiency (new order: 1 - 15F9|20A3 - 20F) is heterozygous lethal. # Tp(1;1)biD1: Transposition (1;1) bifid cytology: Break in 4C5-6; insertion of extra band. origin: X ray induced. references: Banga, Bloomquist, Brodberg, Pye, Larrivee, Mason, Boyd, and Pak, 1986, Chromosoma 93: 341-46. genetics: Mutant for bi. Male lethal. #*Tp(1;1)ct6a1: Transposition (1;1) cut cytology: Tp(1;1)7B2-C1;19;20F. new order: |1 - 7B2|(19 - 20)|7C1 - 19|20F|. Nucleolus organizer included in transposed piece. origin: X ray induced in R(1)2. references: Hannah, 1949, Proc. Intern. Congr. Genet., 8th., pp. 588-89. Hannah-Alava, 1971, Mol. Gen. Genet. 113: 191-203. genetics: Variegated for ct. Male lethal. # Tp(1;1)f67a: see In(1)f67a # Tp(1;1)FN201 cytology: Tp(1;1)3A3-4;5D;8F. discoverer: Lefevre. references: Young and Judd, 1978, Genetics 88: 723-42. genetics: Mutant for z (za-like). # Tp(1;1)hi11: see In(1)hi11 # Tp(1;1)L2 cytology: Tp(1;1)3A2-3;8D;10B1-2. new order: 1 - 3A2|8D - 10B1|3A3 - 8D|10B2 - 20. origin: X ray induced. discoverer: Lefevre. genetics: Homozygous lethal. Mutant for gt and lz. # Tp(1;1)l272-13: see In(1)272-13 # Tp(1;1)lz144: Transposition (1;1) lozenge cytology: Tp(1;1)8E;20F. Transposition of NO to 8E. discoverer: Green and Green, 1956. synonym: lz144A of Ives (Green). references: Hannah-Alava, 1971, Mol. Gen. Genet. 113: 191-203. genetics: lzs phenotype. # Tp(1;1)lz491 cytology: Tp(1;1)8D;20F. Transposition of NO to 8D. discoverer: Green and Green, 1956. references: Hannah-Alava, 1971, Mol. Gen. Genet. 113: 191-203. genetics: lzs phenotype. Recombination reduced in sn-lz and lz-v regions (Green). #*Tp(1;1)N264-63: Transposition (1;1) Notch cytology: Tp(1;1)3C7-9;13C7-8;19F (Hoover). origin: X ray induced. discoverer: Demerec, 38e. genetics: Mutant for N but not for w, rst, or dm. # Tp(1;1)sc260-25: see In(1LR)sc260-25 # Tp(1;1)Si1: Transposition (1;1) Simmons cytology: Tp(1;1)11A8-9;14D1-2;19C. new order: 1A - 11A8-9|(14D1-2 - 19C)|11A8-9 - 14D1-2|19C - 20F. origin: Induced by hybrid dysgenesis. references: Simmons, Raymond, Culbert, and Laverty, 1984, Genetics 107: 49-63. genetics: Chromosome has lethal at r locus. # Tp(1;1)Si2 cytology: Tp(1;1)1A1-8;14D2-E1;18F. new order: 1A1 - 8|14D2-E1 - 18F|1A1-8 - 14D2-E1|18F - 20F. origin: Induced by hybrid dysgenesis. references: Simmons, Raymond, Culbert, and Laverty, 1984, Genetics 107: 49-63. genetics: Chromosome has lethal at r locus. # Tp(1;1)snS93: Transposition (1;1) singed cytology: Tp(1;1)7B5-6;7D1;8D. new order: 1 - 7B5|7D2 - 8D|7B6 - 7D1|8D - 20. origin: X ray induced. references: Lefevre and Johnson, 1973, Genetics 74: 633-45. genetics: Shows sn phenotype in combination with sn3. Male lethal. Female heterozygote viable. When the components of the transposition are separated by crossing over in the 7D2-8D region, the deficiency alone (new order: 1 - 7B5|7D2 - 20) behaves as a dominant lethal, whereas the duplication (new order: 1 - 8D|7B6 - 7D1|8D - 20) behaves as a recessive lethal. # Tp(1;1)vN48: Transposition (1;1) vermilion cytology: Tp(1;1)9F;10C3-5;20. origin: Neutron induced. discoverer: Schalet. references: Voelker, Wisely, Huang, and Gyurkovics, 1985, Mol. Gen. Genet. 201: 437-45. genetics: Mutant for v. Males viable, fertile and show addi- tional mutant phenotypes such as rough eyes, missing bristles, and abnormal wings (Schalet). Females heterozygous for Df(1)v64f, Df(1)v-L1, and Df(1)v-L2 are viable and show the additional mutant phenotypes described for males, but females heterozygous for Df(1)v-L15, Df(1)N71, or Df(1)m259-4 are lethal. # Tp(1;1)z+52 cytology: Tp(1;1)3C;10A;11A. references: Gelbart, 1971, Ph.D. Thesis, University of Wiscon- sin. # Tp(1;1)z+55 cytology: Tp(1;1)3B-C;17F;20A. references: Gelbart, 1971, Ph.D. Thesis, University of Wiscon- sin. # Tp(1;Y) origin: X ray induced. references: Stewart and Merriam, 1973, DIS 50: 167-69. transposition cytology genetics _______________________________________________ Tp(1;Y)B3 3C2-3 viable, fertile Tp(1;Y)B4 1F;3C viable, fertile Tp(1;Y)B11 1B;4A viable, fertile Tp(1;Y)B27 2B viable, fertile Tp(1;Y)B33 ( 3C2;12E7-8;20 viable, fertile Tp(1;Y)L3 9C;9D viable, fertile Tp(1;Y)P11 10C viable, fertile Tp(1;Y)P11a 10C lethal ( New order: 1 - 3C2|12E7-8 - 3C2|20; YL|12E7-8 - 20|YS. 3C break between w and rst (Young and Judd, 1978, Genetics 88: 723-42). # Tp(1;2)25 cytology: Euchromatic portion of left arm of X transposed into heterochromatic region of 2. discoverer: Lindsley. references: Shoup, 1967, J. Cell Biol. 32: 663-75. genetics: Males sterile; sperm heads fail to differentiate and do not convert lysine-rich to arginine-rich histone. # Tp(1;2)26 origin: X ray induced in R(1)2. discoverer: Pontecorvo, 1941. synonym: T(Xc2;2)26. references: 1942, DIS 16: 65. genetics: Section of X including car and bb inserted into base of 2L. Homozygous lethal. # Tp(1;2)51b cytology: Tp(1;2)3C1-2;3D6-E1;20A;52E. new order: 1 - 3C1|20A - 3E1|20A - 20F; 21 - 52E|(3C2 - 3D6)|52E - 60. origin: X ray induced in In(1)wm4 = In(1)3C1-2;20A. discoverer: Lefevre, 51b7. synonym: T(1;2)w+51b7. references: 1951, DIS 25: 71. 1952, DIS 26: 66. Ratty, 1954, Genetics 39: 513-28. Lefevre, 1970, DIS 45: 39. genetics: Segregant Dp(1;2)51b = Dp(1;2)3C1-2;3D6;52E survives; duplicated for loci of w, rst, spl, fa, and dm. Duplication used to cover lethality of N in studies of pseudoallelism at the N locus (Welshons and Von Halle, 1962, Genetics 47: 743- 59). #*Tp(1;2)A50b: Translocation (1;2) from Austin cytology: Tp(1;2)2B;15F;41; inferred from fig. 17H of Mackensen (1935). new order: 1 - 2B|15F - 20; 21 - 41|15F - 2B|41 - 60. references: Mackensen, 1935, J. Heredity 26: 163-74 (fig.). genetics: Left break in X between br and pn; right break between r and f. Mutant for f. #*Tp(1;2)A106 cytology: Tp(1;2)6-7;12;17; rough estimates of breakpoints in X from fig. 17I of Mackensen (1935); chromosome 2 broken in euchromatin of left arm. new order: 1 - 6|17 - 20; 21 - ?|12 - 17|7 - 12|? - 60. references: Mackensen, 1935, J. Heredity 26: 163-74 (fig.). genetics: Mutant for Bx. #*Tp(1;2)A124 cytology: Tp(1;2)10A;13A1-2;59. new order: 1 - 10A|13A2 - 20; 21 - 59|(10A - 13A1)|59 - 60. origin: X ray induced. references: Mackensen, 1935, J. Heredity 26: 163-74 (fig.). Patterson, Stone, and Bedichek, 1935, Genetics 20: 259-79 (fig.). 1937, Genetics 22: 407-26. Pipkin, 1940, Texas Univ. Publ. 4032: 126-56. genetics: Left break between ras and v; right break between g and pl. Male fertile. The segregant Dp(1;2)A124 = Dp(1;2)10A;13A1-2;59, which is duplicated for v+ through g+, survives as a fairly viable and fertile female, but male car- rying Dp(1;2)A124 dies as embryo. The complementary Df(1)A124 = Df(1)10A;13A1-2 survives as a fertile X/X/Df triploid female and as an X/X/Df diploid metafemale but not as an X/Df diploid. #*Tp(1;2)BDG: Transposition (1;2) Bar of Dubinin and Goldat cytology: Tp(1;2)4;15F-16A;20;40-41; inferred from figure of Dubinin and Goldat. new order: 1 - 4|15F - 4|20; 21 - 40|(16A - 20)|41 - 60. origin: X ray induced. references: Dubinin and Goldat, 1936, Biol. Zh. 5: 881-84 (fig.). genetics: Position effect for B. Male lethal. # Tp(1;2)C84 cytology: Tp(1;2)3F;17E-F;30A. new order: 1 - 3F|17F - 20; 21 - 30A|3F - 17E|30A - 60. origin: X ray induced. references: Roberts, 1970, Genetics 65: 429-48. genetics: Male viable and sterile. Recombination reduced in X and 2L. #*Tp(1;2)ct7c1: Transposition (1;2) cut cytology: Tp(1;2)7B2-3;8E2-3;25C superimposed on R(1)1A3- 4;19F-20A1. new order: |1A4 - 7B2|8E2 - 20.20F - 20A1|; 21 - 25C|(7B3 - 8E2)|25C - 60. origin: X ray induced in R(1)2. discoverer: Hannah, 1947. genetics: Mutant for ct but not cm or sn; male lethal. Tp(1;2)ct7c1/Dp(1;3)sn13a1 male survives and is fertile, sug- gesting that lethality is associated with 7B2-3 breakpoint. The segregant Dp(1;2)ct7c1 = Dp(1;2)7B2-3;8E2-3;25C survives; duplicated for sn but not cm; male and female have darker, roof-like wings, enlarged abdomens, and are sterile. #*Tp(1;2)ct14a2 cytology: Tp(1;2)7B2-4;19-20;41E1-2 superimposed on R(1)1A3- 4;19F-20A1. new order: |1A4 - 7B2|20.20F - 20A1|; 21 - 41E1|7B4 - 19|41E2 - 60. origin: X ray induced in R(1)2. discoverer: Hannah, 1947. genetics: Mutant for ct but not cm, sn, or oc. Male lethal. Tp(1;2)ct14a2/Dp(1;3)sn13a1 male rarely survives, probably sterile. #*Tp(1;2)f257-15: Transposition (1;2) forked cytology: Tp(1;2)13E9-10;15E2-3;24F (Sutton). origin: X ray induced. discoverer: Demerec, 35a. genetics: Mutant for f but not M(1)15D or B. Male lethal. # Tp(1;2)GF325 cytology: Tp(1;2)2B7;7D;36C. origin: X ray induced. discoverer: Lefevre. genetics: Homozygous lethal. Mutant for br. #*Tp(1;2)l-v47: Transposition (1;2) lethal-variegated cytology: Tp(1;2)8F-9B; heterochromatic material inserted in X; genetic results suggest linkage between X and 2. origin: X ray induced. references: Lindsley, Edington, and Von Halle, 1960, Genetics 45: 1649-70. genetics: Variegated for a lethal; gg-like phenotype. #*Tp(1;2)ltm16: Transposition (1;2) light-mottled cytology: Tp(1;2)11A;12F;22D;40B-F. new order: 1 - 11A|12F - 20; 21 - 22D|11A - 12F|40B - 22D|40F - 60. origin: X ray induced. references: Hessler, 1958, Genetics 43: 395-403. genetics: Variegated for lt. # Tp(1;2)mv: Transposition (1;2) miniature-variegated cytology: Tp(1;2)7C;10F;40-41. origin: X ray induced. references: Lefevre, 1969, Genetics 63: 589-600. genetics: Deficiency segregant lethal in heterozygous female. Duplication segregant Dp(1;2)mv variegates for m; does not carry fw. #*Tp(1;2)N264-50: Transposition (1;2) Notch cytology: Tp(1;2)3C7-9;20C1-F;22A2-3 (Hoover). new order: 1 - 3C7|20F; 21 - 22A2|3C9 - 20C1|22A3 - 60. origin: X ray induced. discoverer: Demerec, 37k. references: 1941, Proc. Intern. Congr. Genet., 7th., pp. 99- 103. genetics: Variegates for fa but not w, rst, or dm. # Tp(1;2)OR9: Transposition (1;2) from Oak Ridge cytology: Tp(1;2)3A;14F;41. new order: 1 - 3A|14F - 20; 21 - 41|14F - 3A|41 - 60. origin: X ray induced in y. discoverer: Warters, 1959. genetics: Male lethal; lethality not covered by BSw+Y; there- fore, not associated with break at 3A. # Tp(1;2)pn1: Transposition (1;2) prune cytology: Tp(1;2)2E1-2;20A1-2;20D;43F (Slobodyanyuk and Serov, 1983). new order: 1 - 2E1|20D - 20F; 21A - 43F|20A2 - 20D|2E1 - 20A1|43F - 60F. references: Ilyina, Sorokin, Belyaeva, and Zhimulev, 1980, DIS 55: 205. Slobodyanyuk and Serov, 1983, Mol. Gen. Genet. 192: 372-77. genetics: Homozygous lethal. Heterozygotes with pn are pn. # Tp(1;2)r+75c: Transposition (1;2) rudimentary-wild type cytology: Tp(1;2)14B13;15A9;35D-E. new order: 1 - 14B13|15A9 - 20; 21 - 35D|14B13 - 15A9|35E - 60. origin: X ray induced. discoverer: Lefevre. references: Craymer and Roy, 1980, DIS 55: 200-04. Ganetzky and Wu, 1982, Genetics 100: 597-614. genetics: "Pebbly" eyes (Craymer and Roy, 1980) is the result of a sl mutation associated with the distal X breakpoint at 14B13 (Schalet, 1986, Mutat. Res. 163: 115-44). Dp(1;2) segregant covers l(1)14Cc (Jones and Rubin, 1990, Neuron 4: 711-23), probably through lethals in 15A. # Tp(1;2)rb+71g: Transposition (1;2) ruby-wild type cytology: Tp(1;2)3F3;5E8;23A15. new order: 1 - 3F3|5E8 - 20. 21 - 23A15|3F3 - 5E8|23A15 - 60. origin: X ray induced. discoverer: Lefevre. synonym: T(1;2)A1125. references: Craymer and Roy, 1980, DIS 55: 200-04. Busson, Gans, Komitopoulou and Masson, 1983, Genetics 105: 309-25. genetics: Females heterozygous for the deficiency segregant and males carrying the duplication segregant are lethal (Busson et al., 1983). Duplication carries wild-type alleles of vs (Craymer and Roy, 1980), l(1)5CDa (Voelker and Wisely, 1982, DIS 58: 150-51), and ovo (Oliver, Perrimon, and Mahowald, 1987, Genes Dev. 1: 913-23). # Tp(1;2)sc19: Transposition (1;2) scute cytology: Tp(1;2)1B1-2;1B4-5;25A3-7 (Lefevre; Garcia-Bellido, 1979). new order: 1A - 1B1|1B5 - 20; 21 - 25A|(1B2 - 1B4)|25A - 60. origin: X ray induced. discoverer: League. references: Muller, 1935, Genetica 17: 237-52. Garcia-Bellido and Santamaria, 1978, Genetics 88: 469-86. Garcia-Bellido, 1979, Genetics 91: 491-520. genetics: Mutant for sc, showing slight suppression of scutel- lar chaetae (Garcia-Bellido and Santamaria, 1978). A small subterminal piece of X is inserted into 2L one or two units to the right of dp. The two halves of the transposition can be recovered independently as Df(1)sc19 and Dp(1;2)sc19. Homozy- gous clones in wing survive but fail to differentiate sensilla (Schubiger and Palka, 1985, Dev. Biol. 108: 399-410). Df(1)sc19 is deficient for y, ac, sc, and scl but not l(1)1Ac, om, or M(1)1B; it is male lethal but survives in the heterozy- gous female. Dp(1;2)sc19 carries, in addition to sc19, normal alleles of y, ac, and scl; it is viable homozygous and does not affect crossing over in 2L. X-ray-induced losses of y+ from the transposed fragment are M and male and female sterile (Velissariou and Ashburner, 1980, Chromosoma 77: 13-27). molecular biology: 1B4-5 breakpoint at coordinate -13.1 (Car- ramolino, Ruiz-Gomez, Guerrero, Campuzano, and Modolell, 1982, EMBO J. 1: 1185-91). #*Tp(1;2)sc260-27 cytology: Df(1)1A8-B1;19F + T(1;2)15E;33-34;57B-C. new order: 1A1 - 1A8|19F - 20; 21 - 33|15E - 19F|1B1 - 15E|57B - 34|57C - 60. origin: X ray induced. references: Sutton, 1943, Genetics 28: 210-17. genetics: The segregant Df(1)sc260-27 separates as a free duplication from the segregant Dp(1;2)sc260-27, which carries wild-type alleles of y and ac. The transposition as a whole is mutant for sc and male sterile. # Tp(1;2)sn+72d: Transposition (1;2) singed-wild type cytology: Tp(1;2)7A8;8A5;32C;58E. new order: 1 - 7A7|8A6 - 20; 21 - 32C|58E - 32C|(7A8 - 8A5)|58E - 60 (Helfand). origin: X ray induced. discoverer: Lefevre. synonym: T(1;2)FN107. references: Johnson and Judd, 1979, Genetics 92: 485-92. Craymer and Roy, 1980, DIS 55: 200-04. Lefevre, 1981, Genetics 99: 461-80. genetics: Piece of the X carrying ct+ - ptg+ inserted into a pericentric inversion of 2. Males carrying the duplication segregant and a normal X are viable and fertile. Females with the deficiency segregant and a normal X are lethal. # Tp(1;2)v+65b: Transposition (1;2) vermilion cytology: Tp(1;2)10A1;11A7-8;40-41. new order: 1 - 10A1|11A8 - 20; 21 - 40|(10A1 - 11A7)|41 - 60. origin: X ray induced. synonym: T(1;2)65b. references: Lefevre, 1969, Genetics, 63: 589-600. Craymer and Roy, 1980, DIS 55: 200-04. Lefevre, 1981, Genetics 99: 461-80. genetics: Male viable and fertile with v-like eye color and outstretched wings (Lefevre, 1969). #*Tp(1;2)v+63i: see Dp(1;2)v+63i # Tp(1;2)v+75d cytology: Tp(1;2)9A2;10C2;40-41. new order: 1 - 9A1|10C3 - 20; 21 - 40|(9A2 - 10C2)|41 - 60. origin: X ray induced. discoverer: Lefevre. references: Craymer and Roy, 1980, DIS 55: 200-04. genetics: Covers v. # Tp(1;2)w+: Transposition (1;2) white - wild type origin: y w+ f female progeny from cross of Dp(1;1)w+1 or Dp(1;1)w+2 males marked with sc z ec to C(1)DX, y w f females. references: Green, 1984, Mol. Gen. Genet. 194: 275-78. genetics: w+ transposed to 2 (crm+ and rst+ not affected). genetic map transposition position ___________________________ Tp(1;2)w+1 2-24 Tp(1;2)w+4 2-76 Tp(1;2)w+5 2-80 Tp(1;2)w+6 2-31 #*Tp(1;2)w+62g26 cytology: Tp(1;2)2D6-E1;4A1-2;40-41. new order: 1 - 2D6|4A2 - 20; 21 - 40|(2E1 - 4A1)|41 - 60. origin: X ray induced. discoverer: Robins, 62g26. synonym: T(1;A)pn-ec; T(1;2)w62g26. references: Lefevre, 1963, DIS 37: 50. 1970, DIS 45: 39. genetics: No variegation for w+. Male lethal. Deficiency segregant uncovers pn and ec; females carrying the deficiency over a normal X survive, though poorly viable and fertile. Duplication segregant does not cover pn (Lefevre, 1970); males carrying the duplication over a normal X are viable but sterile. # Tp(1;2)w+64b cytology: Df(1)5A1-2;20F [superimposed on In(1)wm4 = In(1)3C1- 2;20F + T(1;2)4E3;26D7, the latter involving the acentric ring concomitant of the Df(1)]. Fragment 3C2 through 5A1-2 broken into two pieces at 4E3 and the pieces, separated by an appre- ciable amount of proximal heterochromatin, inserted into 2L at 26D7. new order: 1 - 3C1|20F - 5A2|20F; 21 - 26D7|4E3 - 3C2|20F|5A1 - 4E3|26D7 - 60. origin: X ray induced in In(1)wm4. discoverer: Lefevre, 64b13. references: 1968, DIS 43: 62-63. Craymer and Roy, 1980, DIS 55: 200-04. genetics: Males carrying the transposition are viable, fertile and wild type. X0 transposition males are viable but show w variegation. Females heterozygous for the deficiency are poorly viable, N, and almost sterile. Males carrying the duplication are lethal, but hyperploid females are viable and fertile (Lefevre, 1968). #*Tp(1;2)wm52b: Transposition (1;2) white-mottled cytology: Tp(1;2)1E5-F1;3C3-5;20F;40-41. new order: 1A - 1E5|20F - 3C5|20F; 21 - 40|(1F1 - 3C3)|41 - 60. origin: X ray induced in In(1)rst3 = In(1)3C3-5;20F. discoverer: Ratty, 52b12. references: Lefevre, 1953, DIS 27: 57. genetics: Variegated for w. Dp(1;2)wm52b survives. #*Tp(1;2)wm53a cytology: Tp(1;2)3B2-C1;3C9-D1;40-41. new order: 1 - 3B2|3D1 - 20; 21 - 40|(3C1 - 3C9)|41 - 60. origin: X ray induced. discoverer: Farnsworth, 53a4. references: Lefevre, 1953, DIS 27: 57. genetics: Variegated for w. The segregant Dp(1;2)wm53a sur- vives and is duplicated for the loci of w, rst, and N. Df(1)w-m53a survives as Notch female; deficient for w, rst, and N. # Tp(1;2)wm258-36 cytology: Tp(1;2)3C6-7;4C2-3;41A-B;41F5-6 (Demerec and Hoover). new order: 1 - 3C6|(41B - 41F5)|4C3 - 20; 21 - 41A|(3C5 - 4C2)|41F6 - 60. Insertions said to be in inverted order but not specified with respect to centromere or numerical order. origin: X ray induced. discoverer: Demerec, 38b. references: Sutton, 1940, Genetics 25: 534-40 (fig.). genetics: Variegated for w and rst but not pn, fa, or dm. Male viable. Cytology predicts that each element of the transloca- tion should survive as aneuploid but not so recorded. # Tp(1;2)w-ec: Transposition (1;2) white-echinus cytology: Tp(1;2)3C1-2;3E7-8;37D. new order: 1 - 3C1|3E8 - 20; 21 - 37D|(3C2 - 3E7)|37D - 60. origin: X ray induced. discoverer: Stafford, 64d20. synonym: T(1;2)(w-ec)64d; T(1;2)NSt; Stafford-Notch; T(1;2)w64d; T(1;2)w-ec. references: Lefevre and Wilkins, 1966, Genetics 53: 175-87. Lefevre, 1968, DIS 43: 63. Lefevre and Moore, 1968, Genetics 58: 557-71. Craymer and Roy, 1980, DIS 55: 200-04. genetics: Males carrying the transposition are viable, w, ec, and N+ (Lefevre and Wilkins, 1966). Females heterozygous for the deficiency show N. Neither the duplication nor the defi- ciency complements wsp (Lefevre, 1968) nor are w ec males or females with the duplication wild type. # Tp(1;2)yR3: Transposition (1;2) yellow of Roberts cytology: Tp(1;2)1B2-3;1E2-3;35F. origin: X ray induced. references: Roberts, 1974, Mutat. Res. 22: 139-44. genetics: Mutant for y. Male viable and fertile. # Tp(1;2;3)pn3: Transposition (1;2;3) prune cytology: Tp(1;2)12E1-2;20A;41A + Tp(1;3)2E1-2;12E1-2;80C. new order: 1A - 2E1|20A2 - 20; 21A - 41A|12E2 - 20A1|41A - 60; 61A - 80C|2E2 - 12E1|80D - 100. origin: X ray induced. references: Ilyina, Sorokin, Belyaeva, and Zhimulev, 1980, DIS 55: 205. Slobodyanyuk and Serov, 1983, Mol. Gen. Genet. 191: 372-77. genetics: Mutant for pn. Homozygous lethal. # Tp(1;3)20A11 cytology: Tp(1;3)5B;17D;81. new order: 1 - 5B|17D - 20; 61 - 81|5B - 17D|81 - 100. origin: Induced by ethyleneimine. references: Lim and Snyder, 1968, Mutat. Res. 6: 129-37. genetics: Male lethal. #*Tp(1;3)A1: Transposition (1;3) from Austin origin: X ray induced. discoverer: Muller, 1926. references: Painter and Muller, 1929, J. Heredity 20: 287-98. genetics: Breakpoints in X chromosome between dm and ec and between car and bb. Midsection of X transposed to 3R. Male hyperploid for Dp(1;f)A1 survives; duplicated for loci of y through dm as well as bb (Schultz). # Tp(1;3)BS3i: Transposition (1;3) Bar-Super inserted in chromosome 3 cytology: Tp(1;3)15F9-16A1;16A7-B1;20F;Y;66B13-C1 (Muller; Lindsley); translocation between Dp(1;1)B = Dp(1;1)15F9- 16A1;16A7-B1 and chromosome 3. X break can be shown geneti- cally to separate f+ from B and is assumed to separate the two halves of the Bar duplication. new order: 1 - 16A7|20F.YS; 61 - 66B13|(16A1 - 20F)|66C1 - 100. Tentative. origin: Neutron induced in X.YS, sc w B. discoverer: Norby. references: Muller and Norby, 1949, DIS 23: 61. genetics: Associated with BS3i. Male viable. Homozygous female lethal. Chromosome 3 containing inserted X material survives as duplication in presence of normal X chromosomes; male sterile; female fertile. Duplication segregant Dp(1;3)BS3i carries bb+ (N. Scott) and has extreme B pheno- type. # Tp(1;3)C92 cytology: Tp(1;3)6E1-2;11D9-10;chrom3 (insertion of 6E1- 2;11D9-10 into 3). origin: X ray induced. references: Lefevre and Peterson, 1972, DIS 48: 126-27. genetics: Mutant for sno. #*Tp(1;3)ct11a: Transposition (1;3) cut cytology: Tp(1;3)1B;7B2-3;8E-F;84B superimposed on R(1)1A3- 4;19F-20A1. new order: |1A4 - 1B|8E - 7B3|8F - 20.20F - 20A1|; 61 - 84B|(1B - 7B2)|84B - 100. origin: X ray induced in R(1)2. discoverer: Hannah, 1947. genetics: Mutant for ct but not y, ac, sc, cm, sn, or oc. Male lethal. Female carrying Dp(1;3)ct11a survives and has small eyes and arc-like wings with delta-like venation; duplicated for cm. #*Tp(1;3)ct12c1 cytology: Tp(1;3)7B2-3;7D2-6;85 superimposed on R(1)1A3-4;19F- 20A1. new order: |1A4 - 7B2|7D6 - 20.20F - 20A1|; 61 - 85|(7B3 - 7D2)|85 - 100. origin: X ray induced in R(1)2. discoverer: Hannah, 1947. genetics: Mutant for ct but not cm or sn. Male lethal. The derived Dp(1;3)ct12c1 survives as female and as sterile male; duplicated for sn. #*Tp(1;3)ct268-31 cytology: Tp(1;3)3D2-3;7B2-5;84D4-5;86B4-C1;88F (Hoover). new order: 61 - 84D4|(3D3 - 7B2)|88F - 100; remainder not described. origin: X ray induced. discoverer: Demerec, 38d. genetics: Mutant for ct and dm but not scp, sn, or fa. Male lethal. # Tp(1;3)ct268-37 cytology: Tp(1;3)5D2-3;7B2-3;80C-F. new order: 1 - 5D2|7B3 - 20; 61 - 80C|7B2 - 5D3|80F - 100. origin: X ray induced. discoverer: Demerec, 39k. references: Sutton, 1940, Genetics 25: 534-40 (fig.). Demerec, 1940, Genetics 25: 618-27. genetics: Mutant for ct; variegated for rux and vs; shf, cm, and sn not affected. The segregant Dp(1;3)ct268-37 viable and fertile in both male and female. Its complement, Df(1)ct268- 37 = Df(1)5D2-3;7B2-3, survives as a Minute female; deficient for M(1)5D6A, rux, vs, shf, and cm but not rg, cx, cv, or sn; mutant for ct. # Tp(1;3)ctJ8 cytology: Tp(1;3)4D1;7B3-4;92A. origin: X ray induced. references: Lefevre and Johnson, 1973, Genetics 74: 633-45. genetics: Male lethal. # Tp(1;3)f+71b: Transposition (1;3) forked-wild type cytology: Tp(1;3)15A4;16C2-3;80-81. new order: 1 - 15A4|16C3 - 20; 61 - 80|15A4 - 16C2|81 - 100. origin: X ray induced. discoverer: Lefevre. synonym: T(1;3)A59; Tp(1;3)71b. references: Craymer and Roy, 1980, DIS 50: 200-04. Ganetzky and Wu, 1982, Genetics 100: 597-614. genetics: The segregant Dp(1;3)f+71b is duplicated for M(1)15D+ - f+. # Tp(1;3)HF308 cytology: Tp(1;3)1E4;12A;81. origin: X ray induced. discoverer: Lefevre. genetics: Male lethal. # Tp(1;3)JC153 cytology: Tp(1;3)16E2-4;17A-B;99D. origin: X ray induced. references: Tanouye, Ferrus, and Fujita, 1981, Proc. Nat. Acad. Sci. USA 78: 6548-52. Baumann, Krah-Jentgens, Muller, Muller-Haltkamp, Seidel, Kecskemethy, Casal, Ferrus, and Pongs, 1987, EMBO J. 6: 3419-29. molecular biology: Maps between 76 and 73 kb distal to the start site of the Sh chromosomal walk (Baumann et al., 1987). # Tp(1;3)m+82f: see Dp(1;3)m+82f # Tp(1;3)N50k: Transposition (1;3) Notch cytology: Tp(1;3)1E3-4;3C6-7;3C8-9;89A. new order: 1A1 - 1E3|3C9 - 20; 61 - 89A|(1E4 - 3C6)|89A - 100. 3C7-8 missing (Lefevre). origin: X ray induced. references: Lefevre, 1951, DIS 25: 71. 1952, DIS 26: 66. Ratty, 1954, Genetics 39: 513-28. genetics: Mutant for N. The segregant Dp(1;3)N50k is viable and carries normal alleles of pn, w, and rst. # Tp(1;3)N264-58 cytology: Tp(1;3)3B2-3;3D6-7;80D-F (Sutton). new order: 1 - 3B2|3D7 - 20; 61 - 80D|3D6 - 3B3|80F - 100. origin: X ray induced. discoverer: Demerec, 38d. synonym: T(1;3)wm264-58. references: 1940, Genetics 25: 618-27. Sutton, 1940, Genetics 25: 534-40 (fig.). Spofford, 1973, DIS 50: 98. genetics: Variegates for w, rst, N, and its pseudoalleles (Cohen, 1962, Genetics 47: 647-59). Spofford, 1973, thinks dm phenotype result of extreme variegation; dm/Dp(1;3)N264-58 males in a Suppressor-of-variegation background are dm+. The segregant Df(1)N264-58 survives in heterozygous female and is deficient for w, rst, fa, and dm but not pn or ec. Dp(1;3)N264-58 survives as both male and female. #*Tp(1;3)N264-100 cytology: Tp(1;3)3B4-C1;4B4-5;80 [Sutton, 1940, Genetics 25: 534-40 (fig.); Gersh, 1959, Genetics 44: 163-72]. new order: 1 - 3B4|4B5 - 20; 61 - 80|4B4 - 3C1|80 - 100. origin: X ray induced. references: Demerec, 1940, Genetics 25: 618-27. genetics: Variegates for w, rst, fa, dm, and ec but not pn or bi. The segregant Df(1)N264-100, which is deficient for N, survives in heterozygous female. Dp(1;3)N264-100 originally survived in female but not male; more recently, male carrying duplication found to survive (Gersh, 1959). # Tp(1;3)O4: Transposition (1;3) of Oliver origin: X ray induced. discoverer: Oliver, 29k24. references: Dobzhansky and Schultz, 1934, J. Genet. 280: 373- 77. Oliver, 1937, DIS 7: 19. genetics: X chromosome broken between m and g and between f and car. Center section of X then inserted into 3L. The segre- gant Df(1)O4 is inviable when added to a normal male genotype, poorly viable when added to a normal female genotype, and sur- vives well when added to a triploid intersex (2X:3A) genotype where it confers a low degree of fertility. The reciprocal segregant, Dp(1;3)O4, is lethal in the male, survives well in the female, and poorly in the intersexes. # Tp(1;3)pn25: Transposition (1;3) prune origin: X ray induced. references: Ilyina, Sorokin, Belyaeva, and Zhimulev, 1980, DIS 55: 205. genetics: Homozygous lethal. Heterozygotes with pn are pn. orientation of transposition cytology inserted segment ______________________________________________________ Tp(1;3)pn25 ( 2E1-2;20A1-2;70A5-6 eucentric Tp(1;3)pn26 2E1-2;20A1-2;70C1-2 eucentric ( See also: Slobodyanyuk and Serov, 1983, Mol. Gen. Genet. 191: 372-77. # Tp(1;3)rasv: Transposition (1;3) raspberry-variegated cytology: Tp(1;3)9E;13C;81F (Lewis). Segment of X with v+ inserted in centric heterochromatin of 3. origin: Fast neutron induced. discoverer: E.B. Lewis. references: Brokaw, 1954, DIS 28: 73. Barr, Valencia, and Plaut, 1968, J. Cell Biol. 39: 8a. Tobler, Bowman, and Simmons, 1971, Biochem. Genet. 5: 111-117 1971, Genetics 68: s67. genetics: Shows recessive variegation for ras and a rough eye and dominant variegation for a wing effect resembling Bg/+. No variegation for m, vb, sd, sl, or un. Is probably an enhancer of B; a few rasv/rasv females somewhat resemble B/+. Dp(1;3)rasv male dies but female survives; duplicated for ras, v, m, dy, and g but not un or r. Tryptophane pyrrolase activity less when v+ in translocated position (Tobler et al., 1971). Df(1)ras-v is lethal in both sexes. #*Tp(1;3)SFV-70k cytology: Tp(1;3)1D1-2;5C5-6;100D4-E1. Segment of X inserted near 3R tip. new order: 1A - 1D1|5C6 - 20; 61 - 100D4|5C5 - 1D2|100E1 - 100F. origin: Induced by ethyl methanesulfonate. references: Lefevre, 1971, DIS 47: 70. genetics: Deficiency segregant dominant lethal. Duplication segregant female viable and fertile but male lethal; duplica- tion carries su(wa)+ through cv+. # Tp(1;3)sn13a1: Transposition (1;3) singed cytology: Tp(1;3)6C;7C9-D1;79D2-E1; material inserted into chromosome 3. new order: |1A4 - 6C|7D1 - 20.20F - 20A1|; 61 - 79D2|(6C - 7C9)|79E1 - 100. origin: X ray induced in R(1)2. discoverer: Hannah, 1947. references: Valencia, 1966, DIS 41: 58. Hall and Kankel, 1976, Genetics 83: 517-35. Lefevre, 1981, Genetics 99: 461-80. genetics: Mutant for sn. The segregant Dp(1;3)sn13a1 survives and is duplicated for cm and ct. # Tp(1;3)sn19Bb5 cytology: Tp(1;3)3C1-2;7C9-10;72A-B superimposed on In(1)1B3- 4;20FL1B2-3;20FR + In(1)4D7-E1;11F2-4. new order: 1A - 1B3|20F - 11F4|4E1 - 7C9|3C1 - 1B3|20F; 61 - 72A|(3C2 - 4D7|11F2 - 7C10)|72B - 100. origin: X ray induced in In(1)scS1Lsc8R + In(1)dl49. references: Valencia, 1966, DIS 41: 58. genetics: Associated with sn19Bb5; w not affected. # Tp(1;3)sta: Transposition (1;3) stubarista cytology: Tp(1;3)1D3-E1;2A;89B21-C4 (Lewis); Tp(1;3)1E1-2;2B3-4;89B21-C4 (Belyaeva et al., 1980). new order: 1A - 1D3|2A - 20; 61 - 89B21|1E1 - 2A|89C4 - 100. origin: X ray induced. discoverer: Oliver, 32l22. references: 1935, DIS 4: 15. Belyaeva, Aizenzon, Semeshin, Kiss, Koczka, Baritcheva, Gorelova, and Zhimulev, 1980, Chromosoma 81: 281-306. genetics: Mutant for sta and ssa. Male viable and fertile; homozygous female lethal. The segregant Dp(1;3)sta is viable. The complementary Df(1)sta is viable in heterozygous female either as Df(1)sta/+; +/+ or as Df(1)sta/Df(1)sta; Dp(1;3)sta/+ but the second type is sterile. Df(1)sta is deficient for su(wa); Dp(1;3)sta carries the su(wa) locus (Rayle and Hoar, 1969, DIS 44: 94). molecular biology: 2B3-4 breakpoint between coordinates 78 and 106.4 (Chao and Guild, 1986, EMBO J. 5: 143-50). # Tp(1;3)v+74c cytology: Tp(1;3)9E3-4;11B12;80-81. new order: 1 - 9E3|11B12 - 20; 61 - 80|(9E4 - 11B12)|81 - 100. origin: X ray induced. discoverer: Lefevre. references: Craymer and Roy, 1980, DIS 55: 200-04. Mortin and Lefevre, 1981, Chromosoma 82: 237-47. genetics: Duplication segregant Dp(1;3)v+74c includes v+ and RpII215+. # Tp(1;3)w68a cytology: Tp(1;3)2F3-4;3C1-2;12A10-B1;12B8-9;77C. Hetero- chromatin inserted adjacent to 3C1. new order: 1 - 2F3|12A10 - 3C2|12B9 - 20. 61 - 77C|het|3C1 - 2F4|77C - 100. Lacks 12B1-8. references: Sorsa, Green, and Beerman, 1973, Nature (London) New Biology 245: 34-37. genetics: Male lethal w variant, viable in compound with Df(1)w258-45 = Df(1)3B2-3;3C2-3; deficient for crm and g. Deficiency segregant lacks z - w and the g region, while the duplication segregant carries the wild-type allele of z but lacks g+. # Tp(1;3)w+ origin: y w+ f female progeny from cross of Dp(1;1)w+1 or Dp(1;1)w+2 males marked with sc z ec to C(1)DX, y w f females. references: Green, 1984, Mol. Gen. Genet. 194: 275-78. genetics: w+ transposed to 3 (crm+ and rst+ not affected). genetic map transposition position ___________________________ Tp(1;3)w+2 3-10 Tp(1;3)w+3 3-28 Tp(1;3)w+7 3-72 #*Tp(1;3)w+54a4 origin: X ray induced. synonym: T(1;3)54a; Dp(1;3)w+54a4. references: Lefevre, 1955, DIS 29: 73. genetics: Section of X including w+ inserted into 3. #*Tp(1;3)w+54c10 origin: X ray induced. synonym: T(1;3)54c; Dp(1;3)w+54c10. references: Lefevre, 1955, DIS 29: 73. genetics: Section of X including w+ inserted into 3. # Tp(1;3)w+67k cytology: Tp(1;3)3A4-5;3E8-F1;8E5;87E17. new order: 1A - 3A4|8E5 - 3F1|8E5 - 20. 60 - 87E17|3A5 - 3E8|87E17 - 100. discoverer: Lefevre, 67k27. synonym: T(1;3)w67k27; duplication segregant: G spot; Tp(1;3)67k. references: Lefevre, 1970, DIS 45: 32. Judd, Shen, and Kaufman, 1972, Genetics 71: 139-56. Craymer and Roy, 1980, DIS 55: 200-04. Gelbart and Wu, 1982, Genetics 102: 179-89. genetics: The duplication segregant carries wild-type alleles of l(1)3Ad through w and N but not ec. It only partially suppresses z, leading to a brownish eye color in z w+ flies (Gelbart and Wu, 1982). # Tp(1;3)wc: Transposition (1;3) white-crimson origin: Believed to be effect of transposing element, the distal part of the w locus being moved to chromosome 3. references: Green, 1969, Genetics 61: 429-41. Paro, Goldberg, and Gehring, 1983, EMBO J. 2: 853-60. genetics: Male with w or Df(1)w is wc. Transposition recessive to w+, complements wsp, and is mutable (Green, 1969). genetic chromosome viability and transposition location of origin fertility of wc _____________________________________________________________ Tp(1;3)wc-1 ( 3-3.8 wc wsp homozygous lethal Tp(1;3)wc-2 3-10.2 wc wsp homozygous viable Tp(1;3)wc-3 3-46 wc wsp (left of ri) Tp(1;3)wc-4 3-92 wc w-67c homozygous viable but male sterile ( In situ hybridization of single copy w DNA to Tp(1;3)wc-1 locates the transposon at 62E; transposon associated with FB elements (Paro et al., 1983). # Tp(1;3)wm49a: Transposition (1;3) white-mottled cytology: Tp(1;3)3A10-B1;3E2-3;80-81. new order: 1 - 3A10|3E3 - 20; 61 - 80|(3B1 - 3E2)|81 - 100. origin: X ray induced. discoverer: Lefevre, 49a7. synonym: T(1;3)wmSp: Translocation (1;3) white-mottled Spot- ted. references: 1949, DIS 23: 59. 1951, DIS 25: 71. Ratty, 1954, Genetics 39: 513-28. genetics: Variegated for w, rst, and spl. The two elements of the translocation can be separated; Df(1)w-m49a survives in heterozygous female and is N; Dp(1;3)wm49a survives in both male and female and carries the loci of w, rst, N, and (from the cytology) presumably dm. # Tp(1;3)wvco: Transposition (1;3) white-variegated cobbled cytology: Tp(1;3)2B17-C1;3C5-6;77D3-5;81 (2C1-2 may not be included in transposed region according to Lefevre). new order: 1A - 2B17|3C6 - 20; 61 - 77D3|2C1 - 3C5|81 - 77D5|81 - 100. discoverer: Clausen. references: Seecof, Kaplan, and Futch, 1971, Proc. Nat. Acad. Sci. USA 62: 528-35. Bowman and Simmons, 1973, Biochem. Genet. 10: 319-31. Lucchesi and Rawls, 1973, Genetics 73: 459-64. Lucchesi, Rawls, and Maroni, 1974, Nature 248: 564-67. Lefevre, 1981, Genetics 99: 461-80. genetics: Insertion of small segment of X with Pgd+, w+, and rst+ into 3 (Lucchesi and Rawls, 1973). Variegated for w and rst and apparently mutant for in but eg not affected; in effect probably associated with 77D3-5 break (Arajarvi and Hannah-Alava, 1969, DIS 44: 73). Each element of the translocation survives as an aneuploid. Df(1)w-vco is defi- cient for recessives from Pgd through w and rst. Df(1)w- vco/Tp(1;3)wvco is w, extreme rst, and highly infertile. Dp(1;3)wvco covers Pgd, w, and rst. # Tp(1;3)wzh: Transposition (1;3) white-zeste halo cytology: Tp(1;3)3C2-3;3C6;61D. origin: Spontaneous derivative of wzm (Judd, 1975). references: Judd, 1975, The Eukaryotic Chromosome (Peacock and Brock, eds.). Australian National University Press, Can- berra, pp. 169-84. Jack and Judd, 1979, Proc. Nat. Acad. Sci. USA 76: 1368-72. Levis, Bingham, and Rubin, 1982, Proc. Nat. Acad. Sci. USA 79: 564-68. genetics: Duplication segregant carries w+, rst+, and vt+. Deficiency segregant male lethal in absence of the duplica- tion. z males and females when homozygous for Tp(1;3)wzh have "halo" eyes (z in center, w+ on periphery) as do z females that are homozygous for Dp(1;3)wzh (Jack and Judd, 1979). z males homozygous for Dp(1;3)wzh, however, have w+ eyes as do z males and females heterozygous for Dp(1;3)wzh. The transposition mutates frequently (Judd, 1975). Some mutations from wzh show changes in the amount and distribution of eye pigment; other mutations involve lethality. molecular biology: According to molecular data (Levis et al., 1982), the white-associated breakpoints of Df(1)w-zh and Dp(1;3)wzh are not identical. Dp(1;3)wzh carries sequenced beginning between the coordinates -3.2 and -1.4 and extending rightward, with 0 the site of the copia insertion in wa. # Tp(1;3)ZWD10 cytology: In(1)4A;20 + Tp(1;3)3C6-7;92B. origin: / ray induced. references: Smolik-Utlaut and Gelbart, 1987, Genetics 116: 285-98. genetics: Male lethal. # Tp(1;3)ZWD13 cytology: Tp(1;3)3C1-3;9B;77E + Tp(1;3)16C;20;94B. origin: / ray induced. references: Smolik-Utlaut and Gelbart, 1987, Genetics 116: 285-98. genetics: Male lethal. #*Tp(1;4)A1: Transposition (1;4) from Austin cytology: Tp(1;4)9B;20;101-102. new order: 1 - 9B|20; 101|9B - 20|102. origin: X ray induced. discoverer: Muller, 1928. synonym: CRB; W13; T(1;4)w13; T(1;4)1. references: Muller and Stone, 1930, Anat. Record 47: 393-94. Muller and Painter, 1932, Z. Indukt. Abstamm. Vererbungsl. 62: 316-65. Painter, 1934, Genetics 19: 448-69. genetics: X chromosome broken between lz and ras and between bb and the centromere. The Df(1)A1 = Df(1)9B;20 segregant dies in the egg stage, showing incomplete blastoderm formation, while the Dp(1;4)A1 = Dp(1;4)9B;20;101-102 segregant dies later in the egg stage without separation of the germ layers (Poulson, 1940, J. Exp. Zool. 83: 271-325). Males with one entire X chromosome plus either segregant die, but females with two entire X's plus either segregant survive with low fertility (Muller and Stone, 1930). Triploid intersexes with either segregant also show very low fertility (Pipkin, 1940, Texas Univ. Publ. 4032: 126-56). #*Tp(1;4)ct13b1: Transposition (1;4) cut cytology: Tp(1;4)7B2-3;20;101A-D superimposed on R(1)1A3- 4;19F-20A1. new order: |1A4 - 7B2|20.20F - 20A1|; 101A|7B3 - 20|101D - 102; Tentative. origin: X ray induced in R(1)2. discoverer: Hannah, 1947. genetics: Mutant for ct but not y, ac, sc, cm, sn, or oc. Male lethal. #*Tp(1;4)N264-86 cytology: Tp(1;4)3C6-7;3C7-8;3E5-6;101F. new order: 1 - 3C7|3E6 - 20; 101A - 101F|3C7 - 3E5|101F - 102; band 3C7 present twice and postulated to have been derived from each of two chromatids in the sperm (Demerec and Sutton, 1940, Proc. Nat. Acad. Sci. USA 26: 532-36). origin: X ray induced. discoverer: Demerec, 39i. references: 1940, Genetics 25: 618-27. Sutton, 1940, Genetics 25: 534-40 (fig.). genetics: Supposedly carries two N loci, one mutant and one variegated. Also carries a mutant allele of rst (rst264-86) and variegates for dm but not w or ec. Carries normal allele of ci+ (Stern). Dp(1;4)N264-86 = Dp(1;4)3C6-7;3E5-6;101F-102 viable and fertile in both sexes; Df(1)N264-86 = Df(1)3C7- 8;3E5-6 viable in heterozygote. # Tp(1;4)w+IV cytology: Tp(1;4)3C2;102F. origin: Activity of transposing element. references: Rasmuson, Montell, Svahlin, and Westerberg, 1980, Mol. Gen. Genet. 177: 567-70. Paro, Goldberg, and Gehring, 1983, EMBO J. 2: 853-60. genetics: Transposition of wspw17g to 4; shows wm phenotype (Rasmuson et al., 1980). molecular biology: Seems to be associated with FB sequences. Located on 4 by in situ hybridization of single copy w DNA close to telomere of 4 at 102F. # Tp(1;4)wm51c: Transposition (1;4) white-mottled cytology: Tp(1;4)3C1-2;3C4-7;20E-F;101. new order: 1 - 3C1|20F - 3C7|20F; 101|(3C2 - 3C4)|101 - 102. origin: X ray induced in In(1)wm4 = In(1)3C1-2;20F. discoverer: Lefevre, 51c20. references: 1951, DIS 25: 71. 1952, DIS 26: 66. Ratty, 1954, Genetics 39: 513-28. genetics: Variegated for w and rst. Male lethal. Dp(1;4)wm51c = Dp(1;4)3C2-3;3C4-7;101 viable and fertile; carries loci of w and rst but not spl. #*Tp(1;4)wm52b13 cytology: Tp(1;4)2A2-3;3C3-4;20F;101. new order: 1 - 2A2|20F - 3C4|20F; 101|(2A3 - 3C3)|101 - 102. origin: X ray induced in In(1)rst3 = In(1)3C3-4;20F. discoverer: Ratty, 52b13. references: Lefevre, 1953, DIS 27: 57. genetics: Variegated for w. #*Tp(2;1)260-31 cytology: Tp(2;1)9A;24;29. new order: 1 - 9A|(24 - 29)|9A - 20; 21 - 24|29 - 60. origin: X ray induced simultaneously with y260-31. discoverer: Fano, 1941. references: Sutton, 1943, Genetics 28: 210-17. genetics: Male lethal; lethality attributable to the indepen- dent mutation to y260-31 since Tp(2;1)260-31, y260-31/ Df(1)sc260-25 is lethal. # Tp(2;1)429.65 cytology: Tp(2;1)20F;21D1-2;25E3-4 (tentative). new order: 1A - 20F|(21D2 - 25E3)|20F; 21A - 21D1|25E4 - 60. discoverer: Gelbart. # Tp(2;1)B19 cytology: Tp(2;1)9B14-C1;24D2-5;25F1-2. new order: 1 - 9B14|25F1 - 24D5|9C1 - 20; 21 - 24D2|25F2 - 60. origin: X ray induced. references: Reuter and Szidonya, 1983, Chromosoma 88: 277-85. Semeshin and Szidonya, 1985, DIS 61: 148-54. Szidonya and Reuter, 1988, Genet. Res. 51: 187-208. genetics: The region transposed carried ed-mid. # Tp(2;1)C121: Transposition (2;1) Crossover suppressor cytology: Tp(2;1)20;35F;40. new order: 1 - 20|(35F - 40)|20; 21 - 35F|40 - 60. origin: X ray induced. discoverer: Roberts, 1965. references: 1970, Genetics 65: 429-48. genetics: Male viable and fertile. Recombination reduced in 2L. # Tp(2;1)C239 cytology: Tp(2;1)7A-B;36C;39E. new order: 1 - 7A|36C - 39E|7B - 20; 21 - 36C|39E - 60. origin: X ray induced. discoverer: Roberts, 1965. references: 1970, Genetics, 65: 429-48. genetics: Male lethal. Recombination reduced in X chromosome. The segregant Dp(2;1)C239 = Dp(2;1)7A-B;36C;39E survives; car- ries His (Moore, Sinclair, and Grigliatti, 1981, Genetics 97: 75-76). # Tp(2;1)DTD2: Transposition (2;1) Disrupter of Transvection at Decapentaplegic cytology: Tp(2;1)20;22D4-5;23B1-2. new order: 1 - 20|(22D5 - 23B1)|20; 21 - 22D4|23B2 - 60. origin: X ray induced. references: Spencer, Hoffmann, and Gelbart, 1982, Cell 28: 451-61. Segal and Gelbart, 1985, Genetics 109: 119-43. genetics: Disrupts transvection at dpp. Df(2L)DTD2 lacks and Dp(2;1)DTD2 carries the entire dpp locus. # Tp(2;1)l-v223 cytology: Tp(2;1)14F;41;50E. new order: 1A - 14F|(41 - 50E)|14F - 20; 21A - 41|50E - 60. origin: X ray induced. discoverer: Lindsley, Edington, and Von Halle. references: 1960, Genetics 45: 1640-70. genetics: Variegated for a lethal and has defective external male genitalia; male sterile. #*Tp(2;1)ltm31 cytology: Tp(2;1)8F;28D;40B-F. new order: 1 - 8F|28D - 40B|8F - 20; 21 - 28D|40F - 60. origin: X ray induced. discoverer: Hessler, 1957. references: 1958, Genetics 43: 395-403. genetics: Variegated for lt. #*Tp(2;1)N264-80 cytology: Tp(2;1)3C6-7;36;40 + In(1)11;20 (Sutton). new order: 1 - 3C6|(36 - 40)|3C7 - 11|20 - 11|20; 21 - 36|40 - 60. origin: X ray induced. discoverer: Demerec, 39d. references: 1941, Proc. Intern. Congr. Genet., 7th., pp. 99- 103. genetics: Contains mutant allele of N but normal alleles of w, rst, dm, and ec. #*Tp(2;1)N264-102 cytology: Tp(2;1)3C6-7;50E;56C (Sutton). new order: 1 - 3C6|(50E - 56C)|3C7 - 20; 21 - 50E|56C - 60. discoverer: Demerec, 39l. genetics: Carries mutant allele of N and normal alleles of w, rst, and dm. # Tp(2;1)odd1.10: Transposition (2;1) odd-skipped cytology: Tp(2;1)4A3-4;21A;24B. new order: 1 - 4A3|(21A - 24B)|4A4 - 20; 21A|24B - 60. discoverer: Nusslein-Volhard. synonym: T(1;2)odd1.10. references: Nusslein-Volhard, Wieschaus, and Kluding, 1984, Wilhelm Roux's Arch. Dev. Biol. 193: 267-82. genetics: Deficiency segregant uncovers odd. # Tp(2;1)OR19 cytology: Tp(1;2)20;51F + In(2R)42B;48E;57C. new order: 1 - 20|51F - 48E|57C - 51F|20; 21 - 42B|48E - 42B|57C - 60E. Three break rearrangement in chromosome 2 deletes 48E-57C and inverts 42B-48E; break between 20 on X and 51F of deleted acrocentric ring. origin: X ray induced. discoverer: Warters, 1961. genetics: Male viable and weakly fertile. Homozygous female viable. Dp(2;1)OR19 = Dp(2;1)20;48E;57C survives in both male and female. #*Tp(2;1)sc260-26 cytology: Tp(2;1)1B4-5;41F2-3;58B2-3 + In(2LR)27D2-3;41A. new order: 1A - 1B4|41F3 - 58B2|1B5 - 20; 21 - 27D2|41A - 27D3|41A - 41F2|58B3 - 60. origin: X ray induced. discoverer: Sutton, 39l. references: 1943, Genetics 28: 210-17. genetics: Mutant for sc but not y, ac, or svr. # Tp(2;1)Scorv23: Transposition (2;1) Scutoid cytology: Tp(2;1)h29;34F1-2;35B1-D1 superimposed on Tp(2;2)Sco. Dp(2;1)Scorv23 visible in salivaries "floating" in the nucleolus (Ashburner et al., 1981). new order: 1 - h29|(34F2 - 35A4|(35C2 - 35C5)|34B4 - 35C1| |35B3 - 35B1)|h29 - h34; 21 - 34F1|35D2 - 60. origin: X ray induced in Tp(2;2)Sco. discoverer: Littlewood. synonym: Tp(2;1)ScoR+23. references: Ashburner, Angel, Detwiler, Faithfull, Gubb, Har- rington, Littlewood, Tsubota, Velissariou, and Walker, 1981, DIS 56: 186-91. Ashburner, 1982, Genetics 101: 447-59. Ashburner, Detwiler, Tsubota, and Woodruff, 1983, Genetics 104: 405-31. Ashburner and Harrington, 1984, Chromosoma 89: 329-37. genetics: Sco revertant; homozygous lethal as transposition. Dp(2;1)Scorv23 homozygotes and hemizygotes are viable and fer- tile; the duplication covers l(2)34Fa - l(2)35Da but not sna or lace, which are exposed by Df(2L)Sco23. The duplication is mutant for noc and is a strong enhancer of H. Df(2L)Sco23 is deficient for l(2)34Fa - lace and is a dominant suppressor of H (Ashburner, 1982). # Tp(2;1)ZWD11 cytology: Tp(2;1)3C7;41;56F. origin: / ray induced. references: Smolik-Utlaut and Gelbart, 1987, Genetics 116: 285-98. genetics: Males w+ and sterile. # Tp(2;?)odd5.1 cytology: Tp(2;Y)23E;24E-F; insertion position not known. origin: X ray induced. discoverer: Nusslein-Volhard. references: Nusslein-Volhard, Kluding, and Jurgens, 1985, Cold Spring Harbor Symp. Quant. Biol. 50: 145-54. genetics: Transposed element carries normal alleles of odd and slp. # Tp(2;?)shvS28: Transposition (2;?) short vein cytology: Tp(2;?)22F1-2;24A1-2 inserted into chromocenter (chromosome arm not known). origin: / ray induced. references: Segal and Gelbart, 1985, Genetics 109: 119-43. genetics: Associated with shvS28. Lethal over shv and lethal dpp alleles. # Tp(2;Y) Table I: Tp(2;Y)b10-4-Tp(2;Y)t223; / ray induced reconstitu- tions of Y and chromosome 2 from T(Y;2); recovered as fertile males in combination with Df(1)bb158. transposition cytology new order ( source ref | comments _______________________________________________________________________________________________________________________________________ Tp(2;Y)b10-4 YL;36D;40A-F y+YS.YLP|40A - 36D|YLDBS; T(Y;2)b10 1, 2, 3 Sd E(SD) in YL of BS.y+ 21A - 36D|40F - 60F. T(2;Y)b10-6 YL;35F;36D y+YS.YLP|36D -35F|YLDBS; T(Y;2)b10 1, 3 21A -35F|36D - 60F. T(2;Y)b10-8 / YL;35F;36D y+YS.YLP|36D - 35F|YLD; T(Y;2)b10 1, 3 21A - 35F|(BS)|36D - 60F Tp(2;Y)b10-9 YL;36D;40A-F y+YS.YLP|40A - 36D|YLDBS; T(Y;2)b10 1, 3 Sd E(SD) in YL of BS.y+ 21A - 36D|40F - 60F. Tp(2;Y)b10-10 YL;36D;40A-F y+YS.YLP|40A - 36D|YLDBS; T(Y;2)b10 1, 3 Sd E(SD) in YL of BS.y+ 21A - 36D|40F - 60F. Tp(2;Y)b10-11 YL;33A;38E-F y+YS.YLP|36D - 33A|38E - 36D|YLDBS; T(Y;2)b10 1, 3 Sd in YL of BS.y+ 21A - 33A|38F - 60F. Tp(2;Y)b10-12 YL;34D-E;37D3-E1 y+YS.YLP|36D - 34E|37D3 - 36D|YLDBS; T(Y;2)b10 1, 3 21A - 34D|37E1 - 60F. Tp(2;Y)b10-20 YL;34A;40A-E y+YS.YLP|36D - 34A|40A - 36D|YLDBS; T(Y;2)b10 1, 3 Sd E(SD) in YL of BS.y+ 21A - 34A|40F - 60F. Tp(2;Y)b10-21 YL;36D;40A-F y+YS.YLP|40A - 36D|YLDBS; T(Y;2)b10 1, 3 Sd E(SD) in YL of BS.y+ 21A - 36D|40F - 60F. Tp(2;Y)b10-22 YL;34A;38B y+YS.YLP|36D - 34A|38B - 36D|YLDBS; T(Y;2)b10 1, 3 Sd in YL of BS.y+ 21A - 34A|38B - 60F. Tp(2;Y)b10-23 YL;36D;40A-F y+YS.YLP|40A - 36D|YLDBS; T(Y;2)b10 1, 3 Sd E(SD) in YL of BS.y+ 21A - 36D|40F - 60F. Tp(2;Y)b10-24 YL;35F;40A-F y+YS.YLP|36D - 35F|40A - 36D|YLDBS; T(Y;2)b10 1, 3 Sd E(SD) in YL of BS.y+ 21A - 35F|40F - 60F. Tp(2;Y)b10-25 YL;35F;40A-F y+YS.YLP|36D - 35F|40A - 36D|YLDBS; T(Y;2)b10 1, 3 Sd E(SD) in YL of BS.y+ 21A - 35F|40F - 60F. Tp(2;Y)b10-26 YL;30B;40F y+YS.YLP|36D - 30B|40F - 36D|YLDBS; T(Y;2)b10 1, 3 Sd E(SD) in YL of BS.y+ 21A - 30B|40F - 60F. Tp(2;Y)b10-27 YL;36D;40A-F y+YS.YLP|40A - 36D|YLDBS; T(Y;2)b10 1, 3 Sd E(SD) in YL of BS.y+ 21A - 36D|40F - 60F. Tp(2;Y)b10-29 YL;36D;38B y+YS.YLP|38B - 36D|YLDBS; T(Y;2)b10 1, 3 Sd in YL of BS.y+ 21A - 36D|38B - 60F. Tp(2;Y)c53 YL;38A3;38E-F y+YS.YLP|38E - 38A3|YLDBS; 3 Sd in YL of BS.y+ 21A - 38A3|38F - 60F. Tp(2;Y)cb50 YL;30C;33E 3 Tp(2;Y)jl3 YS;56C;56F YL.YSP|56C - 56F|YSDy+; T(Y;2)L141 1, 3 21A - 56C|56F - 60F. Tp(2;Y)jl15 YS;55A;57C YL.YSP|56F - 57C|55A - 56F|YSDy+; T(Y;2)L141 1, 3 21A - 55A|57C - 60F. Tp(2;Y)jl21 YS;54A;57B YL.YSP|56F - 57B|54A - 56F|YSDy+; T(Y;2)L141 3 21A - 54A|57B - 60F. Tp(2;Y)jl29 YS;54A;56F YL.YSP|54A - 56F|YSDy+; T(Y;2)L141 3 21A - 54A|56F - 60F. Tp(2;Y)jl34 YS;53D;56F YL.YSP|53D - 56F|YSDy+; T(Y;2)L141 3 21A - 53D|56F - 60F. Tp(2;Y)jl36 YS;53D;57C YL.YSP|56F - 57C|53D - 56F|YSDy+; T(Y;2)L141 3 21A - 53D|57C - 60F. Tp(2;Y)ra38 YL;36B-E;40A-F 3 Sd E(SD) into BS.YL Tp(2;Y)t221 ` YL;36E;37E-F YS.YLP|37E - 36E|YLD; T(Y;2)t22 1, 3 Sd in YL 21A - 36E|(kl?)|37F - 60F. Tp(2;Y)t223 ` YL;33B;36E YS.YLP|36E - 33B|YLD; T(Y;2)t22 1, 3 Sd in YL 21A - 33B|(kl?)|36E - 60F. ( Some material from the Y may be retained within the recon- stituted second chromosome in those new orders with but two breakpoints indicated. | 1 = Lyttle, 1984, Genetics 106: 423-34; 2 = Lyttle, 1986, Genetics 114: 203-16; 3 = Lyttle, 1988. / BS inserted into resealed autosome (Lyttle, 1984). ` Fertility factor(s) inserted into resealed autosome (Lyttle, 1984). Table II: Tp(2;Y)A151-Tp(2;Y)R70; X ray induced in BSYy+. transposition cytology ref ( X/T(Y;2) fertility ______________________________________________________ Tp(2;Y)A151 41;42E-F 1 - Tp(2;Y)B127 49C;49F 2 + Tp(2;Y)B231 27D;31E 2 + Tp(2;Y)D203 47A-B;59 1 - Tp(2;Y)D208 21F;36F 2 + Tp(2;Y)G44 44C;50B 2 - Tp(2;Y)H64 41;57D 2 - Tp(2;Y)J54 35A;40 2 + Tp(2;Y)J64 56F;57A 2 - Tp(2;Y)L12 41A;43E 2 + Tp(2;Y)R31 | 56F;57D 2 - Tp(2;Y)R70 21C3;21C5 1,3 - ( 1 = Baker, 1980, DIS 55: 197; 2 = The Seattle-La Jolla Droso- phila Laboratories, 1971, DIS 47, Suppl. | Df(2;Y)R31 carries Pu+. . # Tp(2;Y)bw+: Transposition (Y;2) brown-wild type cytology: Tp(2;YL);58F1-59A2;60E3-F1 (Gersh, 1956, DIS 30: 115; Nicoletti). new order: YLD|(59A2 - 60E3)|YLP - YS; 21 - 58F1|60F1 - 60F5. origin: X ray induced. discoverer: Dempster. references: Brosseau, Nicoletti, Grell, and Lindsley, 1961, Genetics 46: 339-46. genetics: Dp(2;Y)bw+ carries loci from bw through ba but not hv or M(2)60E; it is used as a marked Y and referred to as bw+Y. Df(2R)bw lost. # Tp(2;Y)C cytology: {Tp(2;Y)41A;43}. Breaks in 2R just to left of 41A (Whittinghill, 1937, DIS 8: 82-84) and distal to cn (located in 43E by Zacharopoulou, Yannopoulos, and Stamatis, 1981, DIS 56: 166-67). origin: X ray induced. discoverer: Dobzansky, 1929. synonym: T(Y;2)C; cn+Y [= Dp(2;Y)C]. references: 1930, Biol. Zentr. 50: 671-85. 1932, Z. Indukt. Abstamm. Vererbungsl. 60: 235-86. Sullivan, Kitos, and Sullivan, 1973, Genetics 75: 651-61. genetics: Duplication segregant Dp(2;Y)C carries cn+ (Sullivan et al., 1973). Translocation heterozygotes over cn viable and fertile, the males with wild-type and the females with cn eyes. # Tp(2;Y)enSF32: Transposition (2;Y) engrailed cytology: Tp(2;Y)48A. references: Kuner, Nakanishi, Ali, Drees, Gustavson, Theis, Kauvar, Kornberg, and O'Farrell, 1985, Cell 42: 309-16. genetics: Homozygous lethal. Associated with enSF32. molecular biology: DNA breakpoint at about -2 kb, i.e., 2 kb to the left of the en1 insertion point. # Tp(2;Y)G cytology: Tp(2;Y)36B5-C1;40F; metaphase chromosomes appear nor- mal (Morgan, Bridges, and Schultz, 1935, Year Book - Carnegie Inst. Washington 34: 287). new order: Y|(36C1 - 40F)|Y; 21 - 36B5|40F - 60. origin: X ray induced. discoverer: Dobzhansky, 1929. references: 1930, Biol. Zentr. 50: 671-85. Rhoades, 1931, Genetics 16: 490-504. Yim, Grell, and Jacobsen, 1977, Science 198: 1168-70. Nakamura, Gay, and Contamine, 1986, Biol. Cell. 56: 227-38. genetics: Dp(2;Y)G has normal phenotype and is fertile when hyperploid in either sex; duplicated for the loci of M(2)36F, M(2)39F, hk, pr, Bl, lt, and bwV32g but not rd; covers the deficiency segregant of Tp(2;Y)b10-4 and includes Sd+ and E(SD)+ (Lyttle, 1986, Genetics 114: 203-16). # Tp(2;Y)G-H1: see Dp(2;Y)H1 # Tp(2;Y)G-H2: see Dp(2;Y)H2 # Tp(2;Y)G-H3: see Dp(2;Y)H3 # Tp(2;Y)G-M15 cytology: Tp(2;Y)36B5-C;37E;40F. Heterochromatin from the Y inserted in the transposed segment of 2. origin: X ray induced in Tp(2;Y)G. new order: Y|36C1 - 37E|Y|37E - 40F|Y; 21 - 36B5|40F - 60. references: Nakamura, 1973, Thesis, Paris-Sud. 1978, Mol. Gen. Genet. 159: 285-92. Nakamura, Gay, and Contamine, 1986, Biol. Cell. 56: 227-38. genetics: Duplication segregant carries M(2)36F+ - hk+ and pr+ - M(2)39F+ but not ref(2)P+. #*Tp(2;Y)H cytology: Tp(2;Y)37B1-2;40B2-3; also an inversion in 2R from near centromere to left of px (Morgan, Bridges, and Schultz, 1935, Year Book - Carnegie Inst. Washington 34: 287). new order: YD|(37B2 - 40B2)|YP; 21 - 37B1|40B3 - | - | - 60. origin: X ray induced. discoverer: Dobzhansky, 1929. references: 1930, Biol. Zentr. 50: 671-85. Schultz and Bridges, 1932, Am. Nat. 66: 323-34. genetics: Male fertile. Homozygote viable and male sterile. Df(2L)H survives and is deficient for M(2)39F, hk, and pr but not M(2)36F or lt; somewhat sterile. Dp(2;Y)H appears normal; duplicated for the loci for which Df(2L)H is deficient. # Tp(2;Y)odd: Transposition (2;Y) odd-skipped discoverer: Nusslein-Volhard. references: Nusslein-Volhard, Wieschaus and Kluding, 1984, Wilhelm Roux's Arch. Dev. Biol. 193: 267-82. Nusslein-Volhard, Kluding, and Jurgens, 1985, Cold Spring Har- bor Symp. Quant. Biol. 50: 145-54. transposition cytology associated with ________________________________________________ Tp(2;Y)odd2.31 ( 21A;25C;38B odd, slp Tp(2;Y)odd4.13 22A;25F odd, mid, slp Tp(2;Y)odd4.25 21A;24D odd, slp ( New order: Y|(21A - 25C)|Y; 21A|38B - 25C|38B - 60. # Tp(2;Y)prC5: Transposition (2:Y) purple origin: Induced by ethyl methanesulfonate. references: Yim, Grell, and Jacobsen, 1977, Science 198: 1168-70. Tobler, Yim, Grell, and Jacobsen, 1979, Biochem. Genet. 17: 197-206. genetics: Variegates for pr. # Tp(2;Y)prd: Transposition (2;Y) paired cytology: Df(2L)33A1-2;34F1-2 Df(2L)33A1-2;34F1-2 + T(Y;2)33F2-3. new order: Y|33F2 - 34F1|33A2 - 33F1|Y; 21 - 33A1|34F2 - 60. synonym: T(Y;2)prd. references: Nusslein-Volhard, Wieschaus, and Kluding, 1984, Wilhelm Roux's Arch. Dev. Biol. 193: 267-82. genetics: Deficiency segregant [Df(2L)prd] uncovers prd - sal. #*Tp(2;Y)R24 cytology: Tp(2;Y)45A;51E. new order: YD|(45A - 51E)|YP; 21 - 45A|51E - 60. origin: X ray induced. discoverer: Slatis. references: 1955, Genetics 40: 8. genetics: Induced simultaneously with (but independently of) bw24, an isoallele of bw. Associated with a rough eye pheno- type. Dp(2;Y)R24-bearing males viable and sterile. # Tp(2;Y)Rsp: Transposition (2;Y) Responder cytology: Insertion of proximal heterochromatin of 2R into BSYy+ between BS and kl5. origin: X-ray-induced reconstitution of intact Y and second chromosomes from T(Y;2)cb25 = T(Y;2)BSXh;41A. references: Lyttle, 1984, Genetics 106: 423-34. Lyttle and Ault, 1985, Genetics 110: s23. Lyttle, 1989, Genetics 121: 751-63. properties: A series of reconstitutions that result in the insertion of variable amounts of 2R heterochromatin into YL and the deletion of that amount from 2R. Both 2R and Y respond independently to SD and in proportion to the number of Rsp sequences that they carry. Each of the segregants, Dp(2;Y)Rsp (=BSRspYy+) or Df(2R)Rsp, survives in the absence of the other and can be studied individually. chromosome cytology genetics kY ( kA ( _____________________________________________________________ Tp(2;Y)Rsp1 h38-h40 l(2)41Aa- 0.804 Tp(2;Y)Rsp4 h38-h44 l(2)41Aa+-l(2)41Af+ 0.956 0.593 Tp(2;Y)Rsp22 h38-h43 l(2)41Aa+-rl+ 0.961 0.514 Tp(2;Y)Rsp24 h38-h39 l(2)41Aa- 0.885 0.479 Tp(2;Y)Rsp29 h38 l(2)41Aa- 0.606 0.998 Tp(2;Y)Rsp31 h38 l(2)41Aa- 0.623 0.979 Tp(2;Y)Rsp42 h38 l(2)41Aa- 0.599 0.973 ( kY is the k value indicating the response to SD of the Responder sequences inserted into the Y, whereas kA reflects the response of the Responder sequences remaining in the recon- stituted second chromosome. # Tp(2;Y)vg76d2 cytology: Tp(2;Y)58B + Dp(2R)58B-D. origin: Caffeine and / rays. references: Alexandrov and Alexandrova, 1987, DIS 66: 185-87. genetics: Mutant for vg. # Tp(2;2)433.56 cytology: Tp(2;2)28D2-3;29E1-2;40-41. new order: 21 - 28D2|29E2 - 40|(28D3 - 29E1)|41 - 60. discoverer: Gelbart. # Tp(2;2)A446 cytology: Tp(2;2)35F1-2;36C1-2;49B1-7 + Df(1)35B1-3;35F1-2. new order: 21 - 35B1|36C2 - 49B1|35F2 - 36C1|49B3 - 60F. origin: X ray induced. discoverer: Aaron. synonym: Df(2L)A446. references: Ashburner, Aaron, and Tsubota, 1982, Genetics 102: 421-35. Gubb, Roote, McGill, Shelton, and Ashburner, 1986, Genetics 112: 551-75. genetics: Df(2L)A446 = Df(2L)35B1-3;35F1-2 is deficient for noc - l(2)35Eb, and heterozygotes are semi-lethal; escapers are sterile and have a wavy-wing and small-fly phenotype. Dp(2;2)A446 (recombinant between Tp(2;2)A446 and a wild-type 2) is viable. # Tp(2;2)b: Transposition (2;2) black origin: / ray induced. references: Alexandrov and Alexandrova, 1986, DIS 63: 159-61. Alexandrova, 1986, DIS 63: 21. genetics: Mutant for b but not for nub or j. Homozygous lethal. transposition cytology _____________________________________ Tp(2;2)b71k1 34D2-4;34D8-E1;43C2-4 Tp(2;2)b79h1 34D2-4;34D8-E1;41 Tp(2;2)b81a 34D2-4;34D8-E1;41D-E1 # Tp(2;2)C123: Transposition (2;2) Crossover suppressor cytology: Tp(2;2)23D-E;38C;39A3. new order: 21A - 23D|38C - 39A3|23E - 38C|39A3 - 60. discoverer: Roberts. synonym: In(2L)C123. references: 1970, Genetics 65: 429-48. genetics: Crossing over reduced in 2L. # Tp(2;2)CA30 cytology: Tp(2;2)26C1;27D1;34A4-B1. origin: / ray induced. discoverer: Ashburner. other information: Recovered with Df(2R)pk78k. # Tp(2;2)dpp: Transposition (2;2) decapentaplegic (W.M. Gelbart) references: Spencer, Hoffmann, and Gelbart, 1982, Cell 28: 451-61. Segal and Gelbart, 1985, Genetics 109: 119-43. Irish and Gelbart, 1987, Genes Dev. 1: 868-79. St. Johnston, Hoffmann, Blackman, Segal, Grimaila, Padgett, Irick, and Gelbart, 1990, Genes Dev. 4: 1114-27. alleles: transposition class origin cytology discov. __________________________________________________________________ Tp(2;2)dpp11 d-III X-ray 22F1-2;29C;32C-D;39B ( Spenser Tp(2;2)dpp13 d-V X-ray 22F1-2;24C1-2;37F;40 | Spenser Tp(2;2)dpp21 d-V X-ray 22A2-3;22F1-2;52F Spenser Tp(2;2)dpp70 d-V /-ray 21A;21D;22F / Segal Tp(2;2)dpp74 d-III /-ray 22F1-2;26A-B;29D-E ` Segal Tp(2;2)dpps7 shv-lc X-ray 22F1-2;24E1-2;25A1-2 Segal ( 21-22F1|32D-39B|22F2-29C|32C-29C|39B-60. | 21-22F1|24C2-37F|22F2-24C1|40-37F|40-60. / 21-21A|22F-21D|21A-21D|22F-60. ` 21-22F1|26B-29D|22F2-26A|29E-60. # Tp(2;2)JHIP1 cytology: Tp(2;2)26A;29B;34D. origin: Spontaneous in JH chromosome line during successive backcrosses. references: Yamaguchi and Mukai, 1974, Genetics 78: 1209-21. # Tp(2;2)Mg: Transposition (2;2) Mglinetz origin: / ray induced. references: Mglinetz, 1971, Genetika (Moscow) 7(8): 108-14. transposition cytology new order ______________________________________________________________ Tp(2;2)Mg5 58F;59D;60E 21-58F|59D-60E|58F-59D|60E-60F Tp(2;2)Mg9 45D;50B;53F 21-45D|50B-53F|45D-50B|53F-60 Tp(2;2)Mg10 33B;35B;40-41 21-33B|35B-40|33B-35B|41-60 # Tp(2;2)MS5: Transposition (2;2) Mglinetz Semenova cytology: Tp(2;2)27D;33A;50F. new order: 21A - 27D|33A - 50F|(27D - 33A)|50F - 60. origin: / ray induced. references: Semenova, Mglinetz, and Glotoff, 1970, Genetika (Moscow) 6(4): 165-69. Mglinetz and Semenova, 1970, Genetika (Moscow) 6(8): 86-94. # Tp(2;2)PurP1: Transposition (2;2) Punch cytology: Tp(2;2)25C-D;40-41;57C4-5. new order: 21 - 25C|41 - 57C4|40 - 25D|57C5 - 60. origin: Induced by ethyl methanesulfonate. references: Mackay and O'Donnell, 1983, Genetics 105: 35-53. Mackay, Reynolds, and O'Donnell, 1985, Genetics 111: 885-904. O'Donnell, Boswell, Reynolds, and Mackay, 1989, Genetics 121: 273-80. genetics: Associated with Pu. Recessive eye color. GTP cyclohydrolase activity lost in eye but present elsewhere. Homozygous lethal. # Tp(2;2)RBR origin: Spontaneous [accumulated on second chromosome lines during repeated backcrossing of In(2LR)bwV1/+ males to In(2LR)bwV1/SM1 females]. references: Yamaguchi, Cardellino, and Mukai, 1976, Genetics 83: 409-22. transposition cytology __________________________________________________ Tp(2;2)RBR3 45F;47C;57D Tp(2;2)RBR33 28C;32D;57A Tp(2;2)RBR49 26E;34A;57C Tp(2;2)RBR66 35B;45F;51E Tp(2;2)RBR117 45A;47F;50F + In(2R)42A;59E Tp(2;2)RBR141 42B;47A;57C # Tp(2;2)Sco: Transposition (2;2) Scutoid cytology: Tp(2;2)35A4-B1;35B3-4;35C1-2;35C5-D1 or In(2L)35A4- B1;35C5-D1 + In(2L)35B3-4;35C1-2. Inferred from cytogenetic data. new order: 21 - 35A4|(35C2 - 35C5)|35B4 - 35C1| 35B3 - 35B1|35D2 - 60. origin: X ray induced. synonym: Sco; Tp(2;2)Sco1 Tp(2;2)Sco2. references: Maroni, 1980, DIS 55: 96-98. Ashburner, Tsubota, and Woodruff, 1982, Genetics 102: 401-20. Ashburner, Detwiler, Tsubota, and Woodruff, 1983, Genetics 104: 405-31. Ashburner and Harrington, 1984, Chromosoma 89: 329-37. genetics: Homozygous lethal. Mutant for Sco, with phenotype enhanced by noc mutations and suppressed by noc+ duplications. AdhF carried on Tp(2;2)Sco. Gene sequence as follows: - noc|[rd - l(2)35Da]| l(2)35Bb - l(2)35Cb|Adh -noc|sna -. molecular biology: Adh-noc region cloned (Chia, Karp, McGill, and Ashburner, 1985, J. Mol. Biol 186: 689-706) (coordinate 0 an EcoRI restriction site 1321 bp to the left of the start of transcription of the larval Adh transcript; positive values toward the centromere). The distal breakpoint of the Sco rearrangement is within the noc gene complex between the nocA and nocB components, such that nocB and nocC are brought into juxtaposition with sna. The molecular coordinates are com- plex, in that the distal break point as judged from the unin- verted portion of noc is between coordinates -103.3 and -102.3; as judged from the noc-sna junction, however, it is between coordinates -108.5 and -107.8 kb, very close to the -107.8 position. Both these breakpoints are between nocA and nocB; the noc-Adh transposed segment extends from -107.8 to at least +40 kb (McGill, Chia, Karp, and Ashburner, 1988, Genet- ics 119: 647-61). The proximal-most breakpoint of Tp(2;2)Sco is within 16 kb to the left of sna (Alberga). # Tp(2;2)Scorv1-DV1 cytology: Tp(2;2)44C3-4;48A5;49F7 superimposed on the In(2LR)35D1-2;44C3-5 revertant of Sco. new order: 21 - 35A4|(35C2 - 35C5)|34B4 - 35C1|35B3 - 35B1| 44C1 - 35D2|48A5 - 49F7|44C4 - 48A5|49F7 - 60|. origin: /-ray induced reversion of the lethal effect of In(2LR)Scorv1 in combination with nocTE35A. references: Ashburner and Harrington, 1984, Chromosoma 89: 329-37. # Tp(2;2)Scorv12: Transposition (2;2) Scutoid-revertant cytology: Tp(2;2)34A4-B1;34F2-4;35E1-2 superimposed on Tp(2;2)Sco. new order: 21 - 34A8|35E1 - 35D2|35B1 - 35B3|35C1 - 35B4| (35C5 - 35C2)|35A4 - 35F4|34B1 - 34F2|35E2 - 60. origin: X ray induced. discoverer: Ashburner. synonym: ScoR+12. references: Ashburner, Faithfull, Littlewood, Richards, Smith, Velissariou, and Woodruff, 1980, DIS 55: 193-95. Ashburner, Detwiler, Tsubota, and Woodruff, 1983, Genetics 104: 405-31. Ashburner and Harrington, 1984, Chromosoma 89: 329-37. genetics: Revertant of Sco. Homozygous lethal. # Tp(2;2)shvS7 Transposition (2;2) shortvein cytology: Tp(2;2)22F1-2;24E1-2;25A1-2. new order: 21A - 22F1|25A1 - 24E2|22F2 - 24E1|25A2 - 60. origin: X ray induced. references: Segal and Gelbart, 1985, Genetics 109: 119-43. genetics: Associated with shvS7. Lethal over shv and lethal dpp alleles. # Tp(2;2)TE35A: Transposition (2;2) Transposable Element cytology: Tp(2;2)35A4-B1;35C1;38F. new order: 21 - 35A4|35C1 - 38F|35B1 - 35C1|38F - 60. origin: / ray induced in TE35A. discoverer: Wilkins. synonym: Tp(2;2)TE146Z. # Tp(2;2)vg: Transposition (2;2) vestigial references: Alexandrov and Alexandrova, 1987, DIS 66: 185-87. phen. transposition cytology origin under 25C __________________________________________________________________ Tp(2;2)vg76j1 49D;49E;50F actinomysin-D + lethal / ray Tp(2;2)vg77d2 49B4;49B5-12;49D2-E 0.35 MeV neutrons vgs Tp(2;2)vg78j1 49D2-3;49D7-E1;50C1-6 / ray vgnw Tp(2;2)vg79b6 49D2;49E1;50C9-14 0.35 MeV neutrons lethal Tp(2;2)vg79f1 36D;41A;49E;53F;54A NaF + / ray lethal Tp(2;2)vg85e2 41B;49E;55F / ray vgnw # Tp(2;3)17 cytology: Tp(2;3)31B1;33F1-2;34A1-2;34D3-4;76B2-C1. new order: 21 - 31B1|33F2 - 34A1|34D4 - 60; 61 - 76B2|34A2 - 34D3|31B1 - 33F1|76C1 - 100. discoverer: Ising. references: Struhl, 1981, Nature 293: 36-41. genetics: Includes esc (Struhl), l(2)34Ca, and l(2)34Db but not l(2)34De - l(2)34Ea or more proximal loci (Ashburner). # Tp(2;3)707 discoverer: Ising. references: Gubb, 1985, Wilhelm Roux's Arch. Dev. Biol. 194: 236-46. genetics: Duplication segregant carries en+. # Tp(2;3)BaG Transposition (2;3) Brista cytology: Tp(2;3)52E;60E;81. synonym: DllG. references: Cohen, Bronner, Kuttner, Jurgens, and Jackle, 1989, Nature 338: 432-34. genetics: Mutant for Ba. molecular biology: 60E breakpoint located on the molecular map. # Tp(2;3)C18: Transposition (2;3) Crossover suppressor cytology: Tp(2;3)25B;40;84B. new order: 21 - 25B|40 - 60; 61 - 84B|25B - 40|84B - 100. origin: X ray induced. discoverer: Roberts, 1964. references: 1970, Genetics 65: 429-48. genetics: Homozygous lethal. Recombination reduced in 2L. # Tp(2;3)C328 cytology: Tp(2;3)55C;58B;80-81; position of breakpoint in chro- mosome 3 with respect to centromere not determined. new order: 21 - 55C|58B - 60; 61 - 80|(55C - 58B)|81 - 100. origin: X ray induced. discoverer: Roberts, 1965. references: 1970, Genetics 65: 429-48. genetics: Homozygous viable. Recombination reduced in 2R. The segregant Dp(2;3)C328 = Dp(2;3)55C;58B;80-81 survives but not the complementary deficiency. # Tp(2;3)CA21 + Tp(3;2)CA20: see Tp(3;2)CA20 # Tp(2;3)Chal7: Transposition (2;3) Choline acetyltransferase cytology: Tp(2;3)41;91C. Complex rearrangement. origin: / ray induced. discoverer: Myers and Gelbart. # Tp(2;3)dp: Transposition (2;3) dumpy cytology: Tp(2;2)27E1-2;32E2-3;45A + Tp(2;3)34D7- E1;41;48A1;80-81 (inferred). Breakpoints listed by Bridges (CP627) have been revised by Woodruff and Ashburner, 1979, who describe a stock obtained from the Bowling Green Stock Center. Examination of the stock by standard genetic tests indicates a transposition between chromosome 2 and chromosome 3. Meta- phase preparations of the balanced stock show, in addition to two normal-looking metaphase chromosomes, a long metacentric and a short submetacentric, believed to be the transposed chromosome. new order: 21 - 27E1|32E3 - 34D7|41 - 34E1|48A1 - 60; 61 - 80|(41 - 45A|27E2 - 32E2|45A - 48A1)|81 - 100. Tentative (Ashburner). Chromosome 3 breaks inferred from genetic data (Muller, 1942; Cooper, Zimmering, and Krivshenko, 1955, Proc. Nat. Acad. Sci. USA 41: 911-14)). origin: Reportedly spontaneous. discoverer: Nichols-Skoog, 36e16. synonym: In(2LR)dp. references: Morgan, Bridges, and Schultz, 1937, Year Book - Carnegie Inst. Washington 36: 301. Curry, 1939, DIS 12: 46. Muller, 1942, DIS 16: 64. Woodruff and Ashburner, 1979, Genetics 92: 133-49. Ashburner, Angel, Detwiler, Faithfull, Gubb, Harrington, Lit- tlewood, Tsubota, Velissariou, and Walker, 1981, DIS 56: 186-91. Ashburner, Aaron, and Tsubota, 1982, Genetics 102: 421-35. genetics: Homozygous lethal. Deficient for b and l(2)34Dd - l(2)34Dg; probably mutant for l(2)34Ea. Mutant for rl, tft and a lethal uncovered by Df(2R)Np. Not necessarily associ- ated with dp36e; semilethal with CyO. May be associated with a dominant rough eye mutation. The chromosome 3 segregant Dp(2;3)dp was said by Muller, 1942, to survive, but to be poorly fertile in males and sterile in females, both sexes having arched wings and low viability. # Tp(2;3)dph27 cytology: Tp(2;3)24F4-7;32B2;91D-E. origin: X ray induced. references: Szidonya and Reuter, 1988a, D15 67: 77-79. 1988b, Genet. Res. 51: 197-208. genetics: Mutant for dp. # Tp(2;3)dpp72: Transposition (2;3) decapentaplegic cytology: Tp(2;3)22F1-2;34B;81F. new order: (Orientation of insertion tentative). 21A - 22F1|34B - 60; 61A - 81F|22F2 - 34B|81F - 100. origin: / ray induced. discoverer: Segal. references: St. Johnston, Hoffmann, Blackman, Segal, Grimaila, Padgett, Irick, and Gelbart, 1990, Genes Dev. 4: 1114-27. genetics: Associated with dppd72, class d-V. # Tp(2;3)DTD33: Transposition (2;3) Disrupter of Transvection at Decapentaplegic cytology: Tp(2;3)22C;25A1-2;85A1-2. new order: 21 - 22C|25A2 - 60; 61 - 85A1|22C - 25A1|85A2 - 100. origin: X ray induced. references: Spencer, Hoffmann, and Gelbart, 1982, Cell 28: 451-61. genetics: Deficiency lacks and duplication carries the entire dpp locus. # Tp(2;3)DTD71 cytology: Tp(2;3)29F;40;89B-C. origin: X ray induced. references: Smolik-Utlaut and Gelbart 1987, Genetics 116: 285-98. # Tp(2;3)en43 Transposition (2;3) cytology: Tp(2;3)46C;48A;81F. new order: 21 - 46C|48A - 60; 61A - 81F|46C - 48A|81F - 100. origin: X ray induced. references: Kornberg, 1981, Proc. Nat. Acad. Sci. USA 78: 1095-99. genetics: Deficiency and duplication segregants for en obtained. # Tp(2;3)en+: Transposition engrailed-wild type cytology: Tp(2;3)47B3;47B9-14;48A1-2;48B-C;62C1. origin: / ray induced. references: Eberlein and Russell, 1983, Dev. Biol. 100: 227- 37. Epper and Sanchez, 1983, Dev. Biol. 100: 387-98. genetics: Deficiency segregant lacks 47B3 to 47B9-14 and 48A1-2 to 48B-C1 and carries In(2R)en28 = In(2R)47B9-14;48A1-2; it is homozygous lethal and cell lethal. The duplication segregant covers all en point mutants. # Tp(2;3)eve1.18: Transposition (2;3) even-skipped cytology: Tp(2;3)44B;46D-E;chrom3. discoverer: Nusslein-Volhard. synonym: T(2;3)eve1.18. references: Nusslein-Volhard, Wieschaus, and Kluding, 1984, Wilhelm Roux's Arch. Dev. Biol. 193: 267-82. genetics: Deficiency segregant uncovers tuf - lin. # Tp(2;3)eve2.28 cytology: Tp(2;3)44F;47A;chrom3. discoverer: Nusslein-Volhard. synonym: T(2;3)eve2.28. references: Nusslein-Volhard, Wieschaus, and Kluding, 1984, Wilhelm Roux's Arch. Dev. Biol. 193: 267-82. genetics: Deficiency segregant uncovers flz - lin in embryos. # Tp(2;3)I: Transposition (2;3) Ising discoverer: Ising. references: Ashburner. transposition cytology new order ___________________________________________________________________________ Tp(2;3)I704 46D;49A;63A-B Tp(2;3)I709 Df(2L)31B2-5;34D6-8; 21 - 31B2|34D8 - 60; + T(2;3)34A1-7;76B5-C1 on 61 - 63C|72E1 - 63C|72E2 - 76B5 In(3L)63C;72E1-2 |34A7 - 34D6| 31B5 - 34A1| 76C1 - 100. Tp(2;3)Me: Transposition (2;3) Moir' cytology: Tp(2;3)48C1-2;59D2-3;60F;80-81 (tentative) + In(3LR)69E;91C + In(3R)89B;97D superimposed on In(3L)63C;72E1-2 (Whittinghill, 1937, DIS 8: 83); breakpoint in chromosome 3 with respect to centromere not determined; new order therefore ambiguous. new order: 21 - 48C1|59D2 - 48C2|60F; 61 - 63C|72E1 - 69E|91C - 97D|89B - 81|59D3 - 60F |80 - 72E2|63C - 69E|91C - 89B|97D - 100. Tentative. origin: X ray induced in In(3L)P, Me. discoverer: Muller, 1930. references: Glass, 1933, J. Genet. 28: 104. genetics: Mutant for sbd (sbd1). Dp(2;3)Me = Dp(2;3)59D2- 3;60F;80-81 survives. # Tp(2;3)ML origin: X ray induced. references: Mukhina and Zhimulev, 1980, DIS 55: 209. genetics: Homozygous lethal. transposition cytology new order _______________________________________________________________ Tp(2;3)ML328 44D;57E;83A1-2 21 - 44C|57E - 60; 61 - 83A1|57E - 44D|83A2 - 100 Tp(2;3)ML473 43A;52B1;89A 21 - 43A|52B1 - 60; 61 - 89A|43A - 52B1|89A - 100 # Tp(2;3)N1-22 cytology: Tp(2;3)46B2-D1;56F9-57A1;64B. new order: 21 - 46B2|57A1 - 60; 61 - 64B|46D1 - 56F9|64B - 100. origin: X ray induced. references: Puro, 1982, DIS 58: 205-08. genetics: Homozygous lethal. # Tp(2;3)odd3.29: Transposition (2;3) odd-skipped cytology: Tp(2;3)21A;25C;100F. synonym: T(2;3)odd3.29. references: Nusslein-Volhard, Kluding, and Jurgens, 1985, Cold Spring Harbor Symp. Quant. Biol. 50: 145-54. genetics: Deficiency segregant uncovers odd and slp in embryos. # Tp(2;3)odd5.1 cytology: Tp(2;3)23E;24E-F;chrom3. synonym: T(2;3)odd5.1. references: Nusslein-Volhard, Wieschaus, and Kluding, 1984, Wilhelm Roux's Arch. Dev. Biol. 193: 267-82. genetics: Deficiency segregant uncovers odd and slp. # Tp(2;3)osp3: Transposition (2;3) outspread cytology: Tp(2;3)35B3-4;36C11-D1;98E2-3. new order: 21 - 35B3|36D1 - 60; 61 - 98E2|35B4 - 36C11|98E3 - 100 (Ashburner). origin: / ray induced. discoverer: Ashburner. references: Chia, Karp, McGill, and Ashburner, 1985, J. Mol. Biol. 186: 689-706. genetics: Associated with osp3. Duplication segregant viable and covers l(2)35Bb to l(2)35De. Deficiency segregant dom- inant lethal. # Tp(2;3)osp204 cytology: Tp(2;3)35B3;86D4-5; deficient for region in 35B. references: Ashburner. genetics: Deficiency segregant uncovers noc-osp. # Tp(2;3)P: Transposition (2;3) Pale cytology: Tp(2;3)58E3-F2;60D14-E2;96B5-C1 (Morgan, Bridges, and Schultz, 1935, Year Book - Carnegie Inst. Washington 34: 286). new order: 21 - 58E3|60E2 - 60F; 61 - 96B5|60D14 - 58F2|96C1 - 100. origin: Spontaneous. discoverer: Bridges, 17j16. references: 1919, Anat. Record 15: 357-58. 1923, Anat. Record 24: 426-27. Bridges and Morgan, 1923, Carnegie Inst. Washington Publ. No. 327: 184-87. Li, 1927, Genetics 12: 1-58. Kossikov and Muller, 1935, J. Heredity 26: 305-17. Bridges, 1937, Cytologia (Tokyo), Fujii Jub., Vol. 2: 745-55. genetics: Associated with P. Homozygote ordinarily lethal but survives in presence of bw+Y = Dp(2;Y)YL;58F1-59A2;60E3-F1; lethality therefore associated with 60D14-E2 breakpoint (Muller, 1942, DIS 16: 64). Dp(2;3)P is viable and fertile; duplicated for loci of px, M(2)58f, crs, bw, mi, abb, pd, ll, l(2)NS, sp, bs, and ba but not a or M(2)60E. Homozygous Dp(2;3)P (i.e., four doses of 59A2-60E3) is lethal unless one chromosome 2 is Df(2R)P. Df(2R)P with two normal third chro- mosomes is lethal. other information: First transposition recorded in D. melanogaster. # Tp(2;3)P32: Transposition (2;3) Pasadena 32 cytology: Df(2R)41A;44C-D + T(2;3)42D-E;89D7-E1. (Transloca- tion involves the acentric ring produced as a concomitant of the deficiency.) new order: 21 - 41A|44D - 60; 61 - 89D7|42D - 41A|44C - 42E|89E1 - 100. origin: X ray induced in bx34e. discoverer: E.B. Lewis, 50i. genetics: Gives transvection effect in Tp(2;3)P32, bx34e/Ubx heterozygote. The segregant Dp(2;3)P32 survives and is fer- tile and virtually wild type; duplicated for stw, ap, tuf, and cn but not ltd. # Tp(2;3)prd2.27: Transposition (2;3) paired cytology: Tp(2;3)31B;33D-E;97C-D. discoverer: Nusslein-Volhard. synonym: T(2;3)prd2.27. references: Nusslein-Volhard, Wieschaus, and Kluding, 1984, Wilhelm Roux's Arch. Dev. Biol. 193: 267-82. Nusslein-Volhard, Kluding, and Jurgens, 1985, Cold Spring Har- bor Quant. Biol. 50: 145-54. genetics: Deficiency segregant [Df(2L)prd2.27)] uncovers bsk - prd. # Tp(2;3)SS301 Transposition (2;3) S. Smith cytology: Tp(2;3)21A;21D1;80F (Ashburner et al., 1980, corrected). origin: X ray induced. discoverer: Smith. references: Ashburner, Faithfull, Littlewood, Richards, Smith, Velissariou, and Woodruff, 1980, DIS 55: 193-95. # Tp(2;3)TE35A-203: Transposition (2;3) Transposable Element cytology: Tp(2;3)34C1-2;35B;80-81 (Ashburner). origin: / ray induced in TE35A. discoverer: Samkanje. synonym: Tp(2;3)TE146Z. genetics: Deficiency segregant dominant lethal. # Tp(2;3)TE35BC-2 cytology: Df(2L)25A1-2;37A1-2 + Tp(2;3)35C1-3;80-81. new order: 21 - 25A1|37A2 - 60; 61 - 80|(35C1 - 25A2|37A1 - 35C3)|81 - 100. origin: / ray induced in TE35BC. discoverer: Gubb. synonym: Tp(2;3)36R. genetics: Variegates for w+ of TE35BC. Does not cover defi- ciency for rst. Lethal with lethal ck alleles. # Tp(2;3)tkv: Transposition (2;3) thick veins cytology: Tp(2;3)25A2-3;25D5-E1;69C. new order: 21 - 25A2|25E1 - 60; 61 - 69C|25A3 - 25D5|69C - 100. discoverer: Szidonya. references: Szidonya and Reuter, 1988, Genet. Res. 51: 197- 208. genetics: Deficiency segregant is M and female sterile; very weak but fertile with SM1 or In(2L)NS, sterile with SM5. # Tp(2;3)V: Transposition (2;3) Valencia origin: X ray induced. references: Valencia, 1970, DIS 45: 37-38. genetics transposition cytology new order ( (homozygotes) __________________________________________________________________ Tp(2;3)V10-7m 26A3;26F;86E 1 lethal Tp(2;3)V12-2-2 44E;50B;80 2 partially viable male sterile Tp(2;3)V13-2a 41A;50C-D;100A-B 3 lethal ( 1 = 21 - 26A3|26F - 60; 61 - 86E|26A3 - 26F|86E - 100. 2 = 21 - 44E|50B - 60; 61 - 80|44E - 50B|80 - 100. 3 = 21 - 41A|50D - 60; 61 - 100A|(41A - 50C)|100B - 100F. # Tp(2;4)X2 cytology: Tp(2;4)23D-E;24A1-2;102D. synonym: Tp(2;4)eyD. references: Ashburner. Tearle and Nusslein-Volhard, 1987, DIS 66: 209-26. genetics: Mutant for Alp2 and eyD. # Tp(3;1)bxd111: Transposition (3;1) bithoraxoid cytology: Tp(3;1)4D;89E;90B2. new order: 1 - 4D|89E - 90B2|4D - 20; 61 - 89E|90B2 - 100. references: Lewis, 1981, Developmental Biology Using Purified Genes (Brown and Fox, eds.). Academic Press, London, New York, San Francisco, Vol. 23, pp. 189-208. genetics: Transposes rightmost part of the BXC to 4D. Mutant for bxd and pbx. Distinguishable from other bxd rearrange- ments by larval phenotype. molecular biology: 89E breakpoint about 5 kb to the left of the right breakpoint of In(3R)Cbxrv1 (Bender, Akam, Karch, Beachy, Peifer, Spierer, Lewis, and Hogness, 1983, Science 221: 23- 29). # Tp(3;1)C152 cytology: Df(3R)88B-C;94A + T(1;3)20;90E.. new order: 1 - 20|(90E - 88C|94A - 90E)|20; 61 - 88B|94A - 100. origin: X ray induced. discoverer: Roberts, 1965. references: 1970, Genetics 65: 429-48. genetics: Male fertile. Recombination reduced in 3R. # Tp(3;1)C210 cytology: Tp(3;1)7F10-8A1;76B;80. new order: 1 - 7F10|76B - 80|8A1 - 20; 61 - 76B|80 - 100. origin: Lefevre. genetics: Associated with gg. # Tp(3;1)DEB8: Transposition (3;1) diepoxybutane cytology: Tp(3;1)20F;70E-F;77C. new order: 1 - 20F|70F - 77C|20F; 61 - 70E|77C - 100. origin: Induced by diepoxybutane. references: Denell, Lim, and Auerbach, 1978, Mutat. Res. 49: 219-24. genetics: Male fertile. # Tp(3;1)FA11 cytology: Tp(3;1)X;84D-E;87D. synonym: T(1;3)FA11. discoverer: Lehman. references: Jurgens, Wieschaus, Nusslein-Volhard, and Kluding, 1984, Wilhelm Roux's Arch. Dev. Biol. 193: 283-95. genetics: Deficiency segregant uncovers hb - sad. # Tp(3;1)HF318 cytology: Tp(3;1)3A3-4;66D-E;80. origin: X ray induced. discoverer: Lefevre. genetics: Hemizygous lethal. # Tp(3;1)KA21 cytology: Tp(3;1)2C9;66B;67E. origin: X ray induced. references: Lefevre, 1981, Genetics 99: 461-80. Oro, McKeown, and Evans, 1990, Nature 347: 298-361. genetics: Hemizygous lethal. Mutant for usp. molecular biology: 2C9 break results in deletion of three nucleotides in usp2. # Tp(3;1)kar5l: Transposition (3;1) karmoisin cytology: Tp(3;1)20;87C7-D1;88E2-3. new order: 1 - 20|87D1 - 88E2|20; 61 - 87C7|88E3 - 100. discoverer: Gelbart. references: Hall and Kankel, 1976, Genetics 83: 517-35. Jurgens, Wieschaus, Nusslein-Volhard, and Kluding, 1984, Wilhelm Roux's Arch. Dev. Biol. 193: 283-95. genetics: Associated with kar. Deficiency segregant uncovers ems - put (Jurgens et al., 1984). Duplication segregant includes trx+ (Ingham, 1981, Wilhelm Roux's Arch. Dev. Biol. 190: 365-69). # Tp(3;1)N264-6: Transposition (3;1) Notch cytology: Breakpoints given in CP627 revised by Ashburner and Walker (Ashburner et al., 1981). X consists of inverted X and inserted third chromosome material; 3 is both inverted and deficient. new order: 1 - 3C|20 - 3C|80 - 73F4|71B8 - 73A5|20F; 61A - 61F5)|71B7 - 61F8|73F1 - 73B2|80 - 100. This cytology incompatible with reported survival of aneuploid segregants. origin: X ray induced. discoverer: Demerec, 33k20. synonym: T(1;3)NN264-6 (CP627). references: CP627. Ashburner, Angel, Detwiler, Faithfull, Gubb, Harrington, Lit- tlewood, Tsubota, Velissariou, and Walker, 1981, DIS 56: 186-91. genetics: Variegates for w and N. X/Y male lethal; X/Y/Y viable and sterile. Duplication segregant viable; deficiency segregant survives and is M. Tp(1;3)N264-6 (CP627). # Tp(3;1)O5 cytology: Tp(1;3)4F2-3;62B-C;88A-C;92C-D (Lewis, 1951, DIS 25: 108-9). Dp(3;1)O5 similar to standard X in size, stain- ing of salivaries, and early completion of replication (Lakho- tia, 1970, Genet. Res. 15: 301-07). new order: 1 - 4F2|88C - 92C|4F3 - 20; 61 - 62B|88A - 62B|92D - 100. origin: X ray induced. discoverer: Oliver, 29l30. references: 1937, Am. Nat. 71: 560-66. 1938, Genetics 23: 162. genetics: Male viable and fertile. Homozygous female viable and sterile. The segregant Dp(3;1)O5 is viable and fertile in male and female. It is duplicated for loci of red, jvl, cv-c, su(Hw), sbd, ss, bx, sr, gl, k, and Dl but not cu, ry, kar, or e (Lindsley and Grell, 1958, DIS 32: 136; Lewis). Produces roughish eyes, spread and nicked wings, coarse bristles, and a darkly-pigmented abdomen. # Tp(3;1)P115: Transposition (3;1) Pasadena 115 cytology: Tp(3;1)20;89B7-8;89E7-8 (S'nchez-Herrero et al., 1985). discoverer: E.B. Lewis. references: Morata and Garcia-Bellido, 1976, Wilhelm Roux's Arch. Dev. Biol. 179: 125-43. S'nchez-Herrero, Vern's, Marco, and Morato, 1985, Nature 313: 108-13. genetics: The deficiency segregant, Df(3R)P115, includes the entire BXC and several neighboring genes (S'nchez-Herrero et al., 1985). The duplication segregant, Dp(3;1)P115, carries all the wild-type alleles in the BXC. # Tp(3;1)pn36 Transposition (3;1) prune cytology: Tp(3;1)1A;2E1-2;61A;62C2-3. new order: 1A|2E1 - 1A|61A - 62C1|2E2 - 20; 61A|62C4 - 100. origin: X ray induced. references: Ilyina, Sorokin; Belyaeva, and Zhimulev, 1980, DIS 55: 205. Slobodyanyuk and Serov, 1983, Mol. Gen. Genet. 191: 372-77. genetics: Mutant for pn. # Tp(3;1)ry35: Transposition (3;1) rosy cytology: Tp(3;1)20;87C-E;91B-C (Lindsley). Left breakpoint in or near ry. new order: 1 - 20|(87E - 91B)|20; 61 - 87C|91C - 100. origin: X ray induced in cu kar chromosome. discoverer: Schalet. references: 1964, DIS 39: 62-64. Schalet, Kernaghan, and Chovnick, 1964, Genetics 50: 1261-68. Roehdanz, Kitchens, and Lucchesi, 1977, Genetics 85: 489-96. genetics: Transposition associated with cu, ry35, and kar. The segregant, Dp(3;1)ry35 is viable and fertile in male and female; duplicated for loci of Aldox, Sb and Ubx. # Tp(3;1)ssv: Transposition (3;1) spineless-variegated cytology: Tp(3;1)20;89B;100F. new order: 1 - 20|89B - 100F|20; 61 - 89B|100F. origin: X ray induced. discoverer: E.B. Lewis. genetics: Variegated for ss1 and mutant for ssa. Male viable and sterile. # Tp(3;1)stg82: Transposition (3;1) scarlet cytology: Tp(3;1)5B6-7;72D10-11;73B1-2;80F; deficient for 72D11-73B1. new order: 1 - 5B6|80F - 73B2|5B7 - 20; 61 - 72D10|80F - 100. origin: X ray induced. discoverer: Belote. references: Belote and McKeown. genetics: Deficient for st. # Tp(3;1)ZWD14 cytology: Tp(3;1)3C1-2;81;86B-C. origin: / ray induced. references: Smolik-Utlaut and Gelbart, 1987, Genetics 116: 285-98. genetics: Males w+; homozygous females show mottled eye color. # Tp(3;Y) origin: X ray induced in BSYy+. X/T(Y;3) transposition cytology ref ( fertility _______________________________________________________ Tp(3;Y)A76 65A;66A 2 + Tp(3;Y)A81 75D;80 2 - Tp(3;Y)B150 88F;94A 2,3 - Tp(3;Y)B162 65E;71A 2 - Tp(3;Y)B204 93B;98B 2,3 + Tp(3;Y)B216 85F;91C 2 Tp(3;Y)B219 94C;100A 2 + Tp(3;Y)B233 67E;70A 2 Tp(3;Y)G63 | 70A;77B-C + 1 + 83C;85A Tp(3;Y)G145 68D;70D 2 + Tp(3;Y)H141 61B;62D 2 + Tp(3;Y)J55 98A;100B 2 - Tp(3;Y)J158 73C;79D 2 Tp(3;Y)L58 88D;93D 1 - Tp(3;Y)L109 / 83D-E;86C;91A-C;95D 2 - Tp(3;Y)L127 ` 99B;99E 2 - Tp(3;Y)P3 61E1;61F7 2 - Tp(3;Y)P6 61A;62A-B ( 1 = Baker, 1980, DIS 55: 197; 2 = The Seattle-La Jolla Droso- phila Laboratories, 1971, DIS 47, Suppl. 3 = Voelker, Ohnishi, and Langley, 1979, Biochem. Genet. 17: 769-83. | Pieces 83C-85A and 70A-77B-C not visibly connected in chromo- center. / New order: YD|(86C - 91A|95D - 91C|83E - 86C)|YP; 61 - 83D|95D - 100. ` Carries Acph+, bv+, and ca+ (Morrison and MacIntyre, 1978, Genetics 88: 487-97). # Tp(3;Y)Abd-B: Transposition (3;Y) Abdominal-B cytology: Tp(3;Y)89C;89E1-2. new order: Y|89C - 89E1|Y; 61 - 89C|89E2 - 100. origin: / ray in mwh stock. references: Tiong, Whittle, and Gribbin, 1987, Development 101: 135-42. genetics: Mutant for Abd-B, Ubx, abd-A; proximal part of Abd-B inserted in Y. molecular biology: Distal breakpoint at +54 kb (Bender) proxi- mal to the Abd-B homeobox. # Tp(3;Y)L131-D3 cytology: Tp(3;Y)72A-B;75C; y+ inserted in 3L. origin: / ray-induced derivative of T(Y;3)L131 that is no longer male-sterile in combinaton with Df(1)bb158. discoverer: Kennison. genetics: Duplication segregant survives and is BS but not y+. # Tp(3;Y)P92: Transposition (3;Y) Pasadena 92 cytology: Tp(3;Y)84D9-10;85A6 on In(3R)85B;88C. Extra bands distally and proximally (B.S. Baker). new order: Y|84D10 - 85A6|Y; 61 - 84D9|85A6 - 85B|88C - 85B|88C - 100. origin: X-ray-induced derivative of In(3R)hbD. discoverer: E.B. Lewis. references: Duncan and Kaufman, 1975, Genetics 80: 733-52. Bender, Turner, and Kaufman, 1986, Dev. Biol. 119: 418-32. genetics: hbD transposed to Y. Duplication segregant comple- ments the recessive lethality of Dfd and covers dsx and pp, but does not cover the Dfd eye phenotype (Duncan and Kaufman, 1975). # Tp(3;2)BTD9 cytology: Tp(3;2)58A;81;88E. new order: 41 - 58A|88E - 81|58A - 60; 61 - 81|88E - 100F. origin: / ray induced. references: Smolik-Utlaut and Gelbart, 1987, Genetics 116: 285-98. # Tp(3;2)C16 cytology: Tp(3;2)50E;66C;70C. new order: 21 - 50E|70C - 66C|50E - 60; 61 - 66C|70C - 100. origin: X ray induced. discoverer: Roberts, 1964. references: 1970, Genetics 65: 429-48. genetics: Homozygous lethal. Recombination reduced in 2R and 3L. # Tp(3;2)C259 cytology: Tp(3;2)40-41;61E;73A; position of breakpoint in chro- mosome 2 with respect to centromere not determined. new order: 21 - 40|61E - 73A|41 - 60; 61A - 61E|73A - 100. Tentative. origin: X ray induced. discoverer: Roberts, 1965. references: 1970, Genetics 65: 429-48. genetics: Homozygous lethal. Recombination reduced in 3L. # Tp(3;2)cav: Transposition (3;2) claret-variegated cytology: Df(3R)81F;99C-E + T(2;3)59D;94. (Translocation involves the acentric ring formed as a concomitant of the deficiency.) new order: 21 - 59D|94 - 99C|81F - 94|59D - 60; 61 - 81F|99E - 100. origin: X ray induced. discoverer: E.B. Lewis. synonym: In(3R)cav (CP627). references: Craymer, 1980, DIS 55: 197-200. genetics: Variegates for ca. # Tp(3;2)CA20 cytology: Df(2L)34D;35C + T(2;3)45A-B;69F-70A;98E-F + T(2;3)48E-F;99E. new order: 21 - 34D|35C - 45A|98F - 99E|48F - 60F; 61 - 69F|98E - 70A|45B - 48E|99E - 100. references: Gubb, Roote, Harrington, McGill, Durrant, Shelton, and Ashburner, 1984, Chromosoma 92: 116-23. genetics: Associated with Df(2L)TE35A-5. # Tp(3;2)Ctx: Transposition (3;2) Cephalothorax cytology: Tp(3;2)35B3-4;83C9-D1;85E5-9 (E.B. Lewis; Jurgens). new order: 21 - 35B3|83D1 - 85E5|35B4 - 60; 61 - 83C9|85E9 - 100. synonym: T(2;3)Ctx. references: Jurgens, Wieschaus, Nusslein-Volhard, and Kluding, 1984, Wilhelm Roux's Arch. Dev. Biol. 193: 283-95. genetics: Mutant for l(2)35Bd and AntpCtx. Deficiency segre- gant uncovers Scr - hb. molecular biology: Third chromosome breakpoint 165-166 kb distal to proximal breakpoint of Tp(3;3)Dfdrv16. # Tp(3;2)DTD129 cytology: Dp(3;2)26F;81F;99A. origin: / ray induced. references: Smolik-Utlaut and Gelbart, 1987, Genetics 116: 258-98. # Tp(3;2)FA12 cytology: Tp(3;2)chrom2;77A-B;80F. synonym: T(2;3)FA12. discoverer: Lehman. references: Jurgens, Wieschaus, Nusslein-Volhard, and Kluding, 1984, Wilhelm Roux's Arch. Dev. Biol. 193: 283-95. genetics: Deficiency segregant uncovers kni and Pc in heterozy- gous embryos. # Tp(3;2)fzC21: Transposition (3;2) frizzled cytology: Tp(3;2)40;66B-D;70D4-7. new order: 21A - 40|66D - 70D4|40 - 60; 61 - 66B|70D7 - 100. origin: / ray induced. discoverer: Adler. genetics: Moderate fz phenotype. Homozygous lethal (occasional homozygotes dying as pharate adults, but most dying earlier). Viable over all other fz alleles. # Tp(3;2)I702 cytology: Tp(3;2)29F;64F;77F on In(3L)63C;72E1-2. new order: 21 - 29F|77F - 72E2|63C - 64F|29F - 60; 61 - 63C|72E1 - 64F|77F - 100. discoverer: Ising. references: Ashburner. # Tp(3;2)iab2P10: Transposition (3;2) infraabdominal 2 - Pasadena 10 cytology: Tp(3;2)29A-C;89C1-2;89E1-2. new order: 21 - 29A|89C2 - 89E1|29C - 60; 61 - 89C1|89E2 - 100. origin: X ray induced. discoverer: Shaw, 1974. synonym: Tp(3;2)P10. references: Lewis, 1978, Nature 276: 565-70. 1980, DIS 55: 207-08. Struhl, 1981, Nature 293: 36-41. 1984, Nature 308: 354-57. Morata, Botas, Kerridge, and Struhl, 1983, J. Embryol. Exp. Morphol. 78: 319-41. Karch, Weiffenbach, Peifer, Bender, Duncan, Celniker, Crosby, and Lewis, 1985, Cell 45: 81-96. genetics: Insertion of ss+-pbx+ and perhaps part of iab2+ into 2L (Lewis, 1978; Struhl, 1984). Homozygous lethal in late embryo (Lewis, 1980). Dp(3;2)P10 homozygous viable; Df(3R)P10 heterozygous viable and Ubx in phenotype. It deletes all the thoracic BXC genes and seems to damage iab2 (Morata et al., 1983). molecular biology: 89E breakpoint 35-36 kb to the right of right breakpoint of In(3R)Cbxrv1. (Karch et al., 1985). # Tp(3;2)iab5301: Transposition (3;2) infraabdominal 5 cytology: Tp(3;2)41;86E;89E. discoverer: R.H. Baker. genetics: Mutant for iab5301. # Tp(3;2)iab5843 cytology: Tp(3;2)23;81;89E3-4. new order: 21 - 23|81 - 89E3|23 - 60; 61 - 81|89E4 - 100. origin: X ray induced. discoverer: R.H. Baker. synonym: iab531616.843. references: Karch, Weiffenbach, Peifer, Bender, Duncan, Cel- niker, Crosby, and Lewis, 1985, Cell 43: 81-96. genetics: Mutant for iab5. molecular biology: 89E3-4 breakpoint 93-99.5 kb to the right of the right breakpoint of In(3R)Cbxrv1. # Tp(3;2)iab5994 cytology: Tp(3;2)22;89B;89E;90A. origin: X ray induced. discoverer: R.H. Baker. synonym: iab531616.994. genetics: Mutant for iab5. # Tp(3;2)MS6: Transposition (3;2) Mglinetz Semenova cytology: Tp(3;2)60A;61C;64B. new order: 21 - 60A|61C - 64B|60A - 60F; 61A - 61C|64B - 100. origin: / ray induced. references: Semenova, Mglinetz, and Glotoff, 1970, Genetika (Moscow) 6(4): 165-69. Mglinetz and Semenova, 1970, Genetika (Moscow) 6(8): 86-94. # Tp(3;2)MS7 cytology: Tp(3;2)21A;61A;63B. new order: 21A|61A - 63B|21A - 60; 61A|63B - 100. origin: / ray induced. references: Semenova, Mglinetz, and Glotoff, 1970, Genetika (Moscow) 6(4): 165-69. Mglinetz and Semenova, 1970, Genetika (Moscow) 6(8): 86-94. # Tp(3;2)N2-27 cytology: Tp(3;2)21F-22A;35D-F;75A-B;80. new order: 21A - 21F|75B - 80|35D - 22A|35F - 60; 61 - 75A|80 - 100. origin: X ray induced. synonym: T(2;3)FM27. references: Puro, Nygren, and Nuutila, 1973, DIS 50: 108. Puro and Nygren, 1975, Hereditas 81: 237-48. Puro, 1982, DIS 58: 205-08. genetics: Homozygous lethal. Duplication segregant survives and carries wild-type alleles of in, ri, and Pc. Deficiency segregant is lethal. # Tp(3;2)osp204: Transposition (3;2) outspread cytology: Tp(3;2)35B2-3;86C2-D4;89A4-7. new order: 21 - 35B2|89A4 - 86D4|35B3 - 60; 61 - 86C2|89A7 - 100. origin: ( ray induced. discoverer: Detwiler. genetics: Deficient for noc-osp but not Adh. Shows stronger Mpe leg phenotype than T(2;3)Mpe, but does not show dominant Mpe wing phenotype. # Tp(3;2)P10: see Tp(3;2)iab2P10 # Tp(3;2)ry+: Transposition (3;2) rosy - wild type cytology: Tp(3;2)2L;87C2-3;88C2-3 (Gelbart). Amount of 87C2-3 material duplicated is uncertain (Gyurkovics). references: Hall and Kankel, 1976, Genetics 83: 517-35. Gausz, Bencze, Gyurkovics, Ashburner, Ish-Horowicz, and Hol- den, 1979, Genetics 93: 917-34. genetics: With Dp(3;2)ry+, Df(3R)kar3J homozygotes or Df(3R)kar3J/Df(3R)kar3l heterozygotes are viable but female sterile, whereas Df(3R)karSz29/Df(3R)kar3J heterozygotes are female fertile (Ish-Horowicz). # Tp(3;2)S485 cytology: Tp(3;2)21C;89F;96A. 89F break believed to be outside the BXC. new order: 21A - 21C|89F - 96A|21C - 60; 61 - 89F|96A - 100. origin: X ray induced. discoverer: Shaw. references: Karch, Weiffenbach, Peifer, Bender, Duncan, Crosby, and Lewis, 1985, Cell 45: 81-96. genetics: Tp(3;2)S485/Df(3R)P9 flies viable and do not show more segmental transformation than Df(3R)P9/+ flies. molecular biology: 89F breakpoint 205-216 kb to the right of right breakpoint of In(3R)Cbxrv1. # Tp(3;2)shvS3: Transposition (3;2) shortvein cytology: Tp(3;2)22F1-2;40C;82A;92A5-8. new order: 21A - 22F1|92A5 - 82A|40C - 22F2|40C - 60F (order of reattach- ment of chromocentral breaks uncertain); 61A - 82A|92A8 - 100F. origin: X ray induced. discoverer: Segal. references: Segal and Gelbart, 1985, Genetics 109: 119-43. genetics: Associated with shv53. Lethal over shv and lethal dpp alleles. # Tp(3;2)SNS cytology: Tp(3;2)33A;90C;92D. origin: / ray induced. references: Sequeira, Nelson, and Szauter, 1989, Genetics 123: 511-24. other information: Induced at same time as ca5. # Tp(3;2)Ubx895: Transposition (3;2) Ultrabithorax cytology: Tp(3;2)2R;89E;90A. origin: X ray induced. discoverer: R.H. Baker, 84k. genetics: Associated with Ubx895. # Tp(3;2)V4-8: Transposition (3;2) Valencia cytology: Tp(3;2)43E;65F;79E-F. new order: 21 - 43E|65F - 79E|43E - 60; 61 - 65F|79F - 100. origin: X ray induced. references: Valencia, 1970, DIS 45: 37-38. genetics: Homozygous lethal. # Tp(3;2)V12-1a cytology: Tp(3;2)55B;88B;91B. new order: 21 - 55B|88B - 91B|55B - 60; 61 - 88B|91B - 100. origin: X ray induced. references: Valencia, 1970, DIS 45: 37-38. genetics: Homozygous lethal. # Tp(3;2)XM54 cytology: Tp(3;2)chrom2;88C2-3;96B11-C1. synonym: T(2;3)XM54. references: Jurgens, Wieschaus, Nusslein-Volhard, and Kluding, 1984, Wilhelm Roux's Arch. Dev. Biol. 193: 283-95. genetics: Deficiency segregant uncovers put - tld in heterozy- gous embryos. # Tp(3;3)bxd100: Transposition (3;3) bithoraxoid cytology: Tp(3;3)66;89B5-6;89E2-3 (89E breakpoint between Ubx and bxd). new order: 61 - 66C|(89B6 - 89E2)|66C - 89B5|89E3 - 100. origin: X ray induced. discoverer: E.B. Lewis. references: 1951, Cold Spring Harbor Symp. Quant. Biol. 16: 159-74. Lewis, 1978, Nature 276: 565-70. Morata and Kerridge, 1981, Nature 290: 778-81. Struhl, 1981, Nature 293: 36-41. Gailey, Jackson, and Siegel, 1982, Genetics 102: 771-82. Struhl, 1984, Nature 308: 454-57. genetics: Transposes small, proximal part of the BXC to 3L. Mutant for bxd and pbx but not bx, Cbx, or Ubx. Dp(3;3)bxd100 survives, and is duplicated for ss - Ubx but not for bxd. Df(3R)bxd100 survives in the heterozygote where it shows the Ubx phenotype. molecular biology: 89E2-3 breakpoint between 15 and 20 kb prox- imal to the distal breakpoint of In(3R)Cbxrv1 (Bender, Akam, Karch, Beachy, Peifer, Spierer, Lewis, and Hogness, 1983, Sci- ence 221: 23-29). # Tp(3;3)bxd110 cytology: Tp(3;3)89E2-3;91D1-2;92A2-3. new order: 61 - 89E2|(91D2 - 92A2)|89E3 - 91D1|92A3 - 100. origin: X ray induced. discoverer: E.B. Lewis. genetics: Transposes the Dl region into the BXC. Mutant for bxd but not bx or Dl. Df(3R)bxd110 = Df(3R)91D1-2;92A2-3, formed by recombination with a normal chromosome in region 89E3-91D1, survives in the heterozygote where it shows the Dl phenotype. The complementary Dp(3;3)bxd110 is duplicated for Dl+ and acts as a suppressor of Dl in Dp(3;3)bxd110/Dl7 heterozygote (Lewis). molecular biology: 89E2-3 breakpoint between 20 and 30 kb prox- imal to the right breakpoint of In(3R)Cbxrv1 (Bender, Akam, Karch, Beachy, Peifer, Spierer, Lewis, and Hogness, 1983, Sci- ence 221: 23-29). # Tp(3;3)bxdDB9 cytology: Tp(3;3)80;89E. origin: X ray induced. discoverer: D. Baker. genetics: Mutant for bxd. # Tp(3;3)C285: Transposition (3;3) Crossover suppressor cytology: Tp(3;3)88F;98B;99B. new order: 61 - 88F|98B - 99B|88F - 98B|99B - 100. origin: X ray induced. discoverer: Roberts, 1965. references: 1970, Genetics 65: 429-48. genetics: Homozygous lethal. Recombination between st and ca sharply reduced. # Tp(3;3)C341 cytology: Tp(3;3)63C;71E;80-81; position of right breakpoint with respect to centromere not determined. new order: 61 - 63C|71E - 80|(63C - 71E)|81 - 100. origin: X ray induced. discoverer: Roberts, 1965. references: 1970, Genetics 65: 429-48. genetics: Homozygous viable. Recombination reduced in 3L. # Tp(3;3)Dfdrv1: Transposition (3;3) Deformed-revertant cytology: Tp(3;3)83D4-5;84A4-5;98E6-F2. new order: 61 - 83D4|84A5 - 98E6|83D5 - 84A4|98F2 - 100. origin: X ray induced. references: Hazelrigg and Kaufman, 1983, Genetics 105: 581- 600. genetics: Revertant of Dfd. # Tp(3;3)Dfdrv16 cytology: Tp(3;3)84A4-5;86F11;87D13-14. new order: 61 - 84A4|86F11 - 87D13|84A5 - 86F11|87D14 - 100. origin: X ray induced. references: Hazelrigg and Kaufman, 1983, Genetics 105: 581- 600. Scott, Weiner, Hazelrigg, Polisky, Pirrotta, Scalenghe, and Kaufman, 1983, Cell 35: 763-76. genetics: Revertant of Dfd. Shows a pic- phenotype (Clark and Chovnick, 1986, Genetics 114: 819-40). molecular biology: DNA breakpoint at 84A4-5 is coordinate 0 in the walk of Scott et al. # Tp(3;3)DlII13: Transposition (3;3) Delta cytology: Tp(3;3)88F5-9;91A3-8;92A2. new order: 61 - 88F5|91A8 - 92A2|88F9 - 91A3|92A2 - 100. origin: X ray induced. dicoverer: Shrons. references: Vassin and Campos-Ortega, 1987, Genetics 116: 433-45. genetics: Associated with DlII13. # Tp(3;3)hm3: Transposition (3;3) hairy cytology: Tp(3;3)61E;66D2-3;66D9-10. new order: 61A - 61E|66D3 - 66D9|61E - 66D2|66D10 - 100. origin: X ray induced. references: Ingham, Pinchin, Howard, and Ish-Horowicz, 1985, Genetics 111: 463-86. genetics: Homozygous lethal. Associated with se and h. molecular biology: 66D break located at -10.8 to -9.35 kb on the DNA map of h (Howard, Ingham, and Rushlow, 1988, Genes Dev. 2: 1037-46); "+" values to the right, "-" values to the left. The coordinate system has 0 at the start of transcrip- tion (Rushlow). # Tp(3;3)H57: Transposition (3;3) Hairless cytology: In(3R)86F7-11;97D1-2 + In(3R)95C1-2;98C5. (Ash- burner). new order: 61 - 86F7|97D1 - 95C2|98C5 - 97D2|86F11 - 95C1 |98C5 - 100. discoverer: Gloor. references: van Breugel, Ray, and Gloor, 1968, Genetica 39: 165-92. Ashburner, 1982, Genetics 101: 447-59. genetics: Associated with H57 (van Breugel et al. 1968), but, presumably, H57 and the transposition arose by independent mutational events (Ashburner, 1982) since none of the break- points is between 92D and 94A, the location of H. # Tp(3;3)iab3277 Transposition (3;3) infraabdominal cytology: Tp(3;3)89E;94A;96F. new order: 61 - 89E|94A - 96F|89E - 94A|96F - 100. origin: X ray induced in Mcp. discoverer: D. Baker. synonym: McprevB277, iab3B277, iab3DB. references: Karch, Weiffenbach, Peifer, Bender, Duncan, Cel- niker, Crosby, and Lewis, 1985, Cell 43: 81-96. genetics: Mutant for iab3. Partial revertant of Mcp. molecular biology: 89E breakpoint 63-64.5 kb to the right of the right breakpoint of In(3R)Cbxrv1. # Tp(3;3)iab6Vno cytology: Tp(3;3)89E;94A;96F. new order: 61 - 89E|94A - 96F|89E - 94A|96F - 100. origin: X ray induced. discoverer: E.H. Grell, 56c. synonym: Tp(3;3)Vno. references: 1959, DIS 33: 94. Karch, Weiffenbach, Peifer, Bender, Duncan, Celniker, Crosby, and Lewis, 1985, Cell 43: 81-96. genetics: Associated with Vno and iab6. Insertion at 89E separable by recombination from the deletion at 94A-96F, the Vno wing phenotype segregating with the deletion (Karch et al., 1985). Homozygous lethal. molecular biology: 89E breakpoint 108-111 kb to the right of the distal breakpoint of In(3R)Cbxrv1. # Tp(3;3)iab8rv transposition cytology _________________________________ Tp(3;3)iab8rv82 64E-F;65A;89E Tp(3;3)iab8rv96 64E-F;65A;89E + Df(3R)80;89E # Tp(3;3)Mg: Transposition (3;3) Mglinetz origin: / ray induced. transposition cytology new order ref ( __________________________________________________________________ Tp(3;3)Mg16 64A;89B;90F 61-64A|89B-90F|64A-89B|90F-100 2 Tp(3;3)Mg25 83C;87A;98A 61-83C|87A-98A|83C-87A|98A-100 3 Tp(3;3)Mg79 72A;90A;93F 61-72A|90A-93F|72A-90A|93F-100 4 Tp(3;3)Mg80 86A;90E;99D 61-86A|90E-99D|86A-90E|99D-100 4 Tp(3;3)Mg197 75A;84A;93F 61-75A|84A-93F|75A-84A|93F-100 1 ( 1 = Mglinetz, 1968, Genetika (Moscow) 4(8): 81-86; 2 = Mglinetz, 1971, Genetika (Moscow) 7(8): 108-14; 3 = Mglinetz, 1972, Genetika (Moscow) 8(2): 82-91; 4 = Mglinetz, 1973, Genetika (Moscow) 9(3): 69-74. # Tp(3;3)MKRS cytology: In(3LR)71B2-C2;92E + Df(3R)87E8-F1;93C; the right inversion breakpoint involves the acentric ring generated by the deficiency. new order: 61 - 71B2|92E - 93C|87F1 - 92E| 71C2 - 87E8|93C - 100. (Hilliker et al., 1980). origin: Insertion of kar into Tp(3;3)MRS. synonym: In(3LR)MKRS. references: Chovnick, Schalet, Kernaghan, and Talsma, 1962, Am. Nat. 96: 281-96. Chovnick, Ballantine, Baillie, and Holm, 1970, Genetics 66: 315-29. Chovnick, 1973, Genetics 75: 123-31. McCarron, Gelbart, and Chovnick, 1974, Genetics 76: 289-99. Hilliker, Clark, Chovnick, and Gelbart, 1980, Genetics 95: 95-110. genetics: Carries M(3)76A, kar, ry2, and Sb. other information: Used as balancer for proximal region of chromosome 3; described as MKRS in the section on balancers. Also exists with kar+ rather than kar, abbreviated MRS. # Tp(3;3)MRS: see Tp(3;3)MKRS # Tp(3;3)MS8: Transposition (3;3) Mglinetz Semenova cytology: Tp(3;3)66C;71E;95C. new order: 61 - 66C|71E - 95C|66C - 71E|95C - 100. origin: / ray induced. references: Semenova, Mglinetz, and Glotoff, 1970, Genetika (Moscow) 6(4): 165-69. Mglinetz and Semenova, 1970, Genetika (Moscow) 6(8): 86-94. # Tp(3;3)P6: see Tp(3;3)P26 # Tp(3;3)P20: see Tp(3;3)UbxP20 # Tp(3;3)P26: Transposition (3;3) Pasadena cytology: Tp(3;3)81F;88B;91C-F(?). synonym: Tp(3;3)P6. references: Craymer. # Tp(3;3)P47 cytology: Tp(3;3)66B;89D;92A. new order: 61 - 66B|(89D - 92A)|66B - 89D|92A - 100. origin: X ray induced. references: Craymer. genetics: Transposition of segment carrying Ubx+-Dl+. Described by Craymer (1984, DIS 60: 80-82). # Tp(3;3)P146: see Tp(3;3)S462 # Tp(3;3)S462: Transposition (3;3) of Shaw cytology: Tp(3;3)64C-E;89D1-2;90D1. new order: 61 - 64C|89D2 - 90D1|64E - 89D1|90D1 - 100. origin: X ray induced. discoverer: Shaw, 1973. synonym: Tp(3;3)P146. references: Lewis, 1980, DIS 55: 207-08. Morata, Botas, Kerridge, and Struhl, 1983, J. Embryol. Exp. Morphol. 78: 319-41. genetics: Entire BXC plus the normal allele of l(3)89Ej (Ivy) transposed to 3L. Transposition is homozygous lethal, but the duplication recombinant Dp(3;3)S462 is homozygous viable. The deficiency segregant Df(3R)S462 survives as a heterozygote but ecloses one or two days later than wild type and is sterile in both sexes (Lewis, 1980). # Tp(3;3)sbd104: Transposition (3;3) stubbloid cytology: Tp(3;3)89B5;89C;91B. new order: 61 - 89B5|89C - 91B|89B5 - 89C|91B - 100. origin: X ray induced. discoverer: E.B. Lewis, 1947. references: 1980, DIS 55: 207-08. Gailey, Jackson, and Siegel, 1982, Genetics 102: 771-82. Struhl, 1984, Nature 308: 454-57. genetics: Associated with sbd104. Homozygous lethal and lethal over Sb. Dp(3;3)sbd104 and Df(3R)sbd104 derivable from Tp(3;3)sbd104/+ by recombination. Df(3R)sbd104 is deficient for sbd-ss but not for the BXC (Lewis, 1980; Struhl, 1984). # Tp(3;3)SMG40 cytology: Tp(3;3)87B;92A;99A. new order: 61 - 87B|92A - 99A|87B - 92A|99A - 100. origin: / ray induced. references: Semenova, Mglinetz, and Glotoff, 1970, Genetika (Moscow) 6(4): 165-69. #*Tp(3;3)sr300.240: Transposition (3;3) stripe cytology: Tp(3;3)75C;89E;92A. new order: 61 - 75C|(89E - 92A)|75C - 89E|92A - 100. Inserted piece said to be in inverted order but not specified whether with respect to numerical sequence or centromere. origin: X ray induced. discoverer: Alexander. references: Ward and Alexander, 1957, Genetics 42: 42-54. genetics: Mutant for sr. Homozygous lethal. # Tp(3;3)Tabrv82: Translocation (3;3) Transabdominal-reverted cytology: Tp(3;3)64F-65A;89E + In(3R)89E;90D. origin: X ray induced in In(3R)Tab. references: Celniker and Lewis, 1987, Genes and Development 1: 111-23. genetics: Revertant of the dominant Tab phenotype. When hemizy- gous, shows stronger transformation of the eighth ventral setal band toward that of the seventh than does Tab/Df(3R)P9; also A7 transformed toward A5 or A6, no posterior spiracles, and no ninth ventral setal band. # Tp(3;3)Tabrv96 cytology: Tp(3;3)80;89E + In(3R)89E;90D. origin: X ray induced in In(3R)Tab. references: Celniker and Lewis, 1987, Genes and Development 1: 111-23. genetics: Revertant of the dominant Tab phenotype. When hemiz- ygous, shows stronger transformation of the eighth ventral setal band toward that of the seventh than does Tab/Df(3R)P9; also, abnormal posterior spiracles, and a rudimentary ninth ventral setal band. molecular biology: Lesion associated with the 89E breakpoint between 170 and 173 kb to the right of the right breakpoint of In(3R)Cbxrv1. # Tp(3;3)th100.293: see In(3L)th100.293 # Tp(3;3)UbxP20: Transposition (3;3) Ultrabithorax-Pasadena 20 cytology: Tp(3;3)68A;68E;89E (corrected by E.B. Lewis). new order: 61 - 68A|68E - 89E|68A - 68E|89E - 100. origin: X ray induced. synonym: Tp(3;3)P20. references: E.B. Lewis, 1980, DIS 55: 207-08. genetics: Associated with UbxP20. Heterozygotes show slight M and seem to have reduced female fertility. Both duplication and deficiency derivable from the transposition. # Tp(3;3)V13: Transposition (3;3) Valencia cytology: Tp(3;3)61F;62A;64C (61F deleted). origin: X ray induced. references: Valencia, 1970, DIS 45: 37-38. genetics: Semi-lethal and sterile. # Tp(3;3)Vno: see Tp(3;3)iab6Vno # Tp(3;4)h+44: Transposition (3;4) hairy - wild type cytology: Tp(3;4)63A3-B1;67A1-2;101F (Jeffery, 1979; Ingham et al., 1981). new order: 61 - 63A3|67A2 - 100; 101A - 101F|63B1 - 67A1|102. origin: X ray induced. references: Jeffery, 1971, DIS 47: 37. 1979, Genetics 91: 105-25. Ingham, Pinchin, Howard, and Ish-Horowicz, 1985, Genetics 111: 463-86. genetics: Homozygous lethal. Heterozygotes over h variegate for h (Jeffery, 1971). Dp(3;4)h+44 carries h+ and is dominant over two doses of h (Ingham et al., 1985). # Tp(4;2)ci+15 cytology: Tp(4;2)30A;101F1;102C4. new order: 21 - 30A|(101F1 - 102C4)|30A - 60F; 101A - 101F1|102C4 - 102F. origin: X ray induced. synonym: R15(+). references: Stern, MacKnight, and Kodani, 1946, Genetics 31: 598-619. Stern and Kodani, 1955, Genetics 40: 343-73. genetics: Tp(4;2)ci+15/ci flies show L4 vein interruptions, whereas ci+/ci flies are wild type. # Tp(4;3)eyD: Transposition (4;3) eyeless-Dominant cytology: Tp(4;3)70C;101-102. new order: 61 - 70C|101 - 102|70C - 100; 101|102. Most of the right arm of chromosome 4 inserted into 3L. origin: X-ray induced derivative of eyD. references: Stern and Tokunaga, 1967, Proc. Nat. Acad. Sci. USA 57: 658-64. genetics: Used in generation of ey+ clones in eyD background by mitotic exchange. + tissue develops non-autonomously with eyD phenotype in basitarsus. # Tp(4;3)f cytology: Tp(4;3)65D;chrom4; at least seven bands of chromosome 4 inserted into 3L (Lewis, 1956, DIS 30: 130). origin: X ray induced. discoverer: Sturtevant, 1930. synonym: T(3;4)104;T(3;4)f. references: Beadle, 1933, Z. Indukt. Abstamm. Vererbungsl. 65: 111-28. James, Eissenberg, Craig, Dietrich, Hobson, and Elgin, 1989, Eur. J. Cell Biol. 50: 170-80. genetics: Homozygous lethal. No ci variegation (Stern). # XO: see R(1)1 # Xc: see R(1)1 # Xc2: see R(1)2