j: jaunty From Bridges and Morgan, 1919, Carnegie Inst. Washington Publ. No. 278: 148. # j: jaunty location: 2-48.7. origin: Spontaneous. discoverer: Bridges, 11l11. references: Bridges and Morgan, 1919, Carnegie Inst. Washington Publ. No. 278: 160 (fig.). Clausen, 1924, J. Exp. Zool. 38: 423-36. Stern, 1927, Biol. Zentralbl. 47: 361-69. phenotype: Distal half of wing upturned but not twisted as in Cy. Curling is strong if wing unfolds at 25-30 but is weak or overlaps wild type if wing unfolds below 25. RK2. alleles: allele origin discoverer ref ( phenotype ______________________________________________________ j1 spont Bridges, 11l11 3, 4, 7 *j2 spont Stern, 25d31 7, 8 j | j63 j67b EMS Grell 5 >j jSF7 EMS Littlewood 2 =j ( 1 = Andrew, 1959, DIS 33: 82; 2 = Ashburner, Faithfull, Littlewood, Richards, Smith, Velissariou, and Woodruff, 1980, DIS 55: 193-95; 3 = Bridges and Morgan, 1919, Carne- gie Inst. Washington Publ. No. 278: 160 (fig.); 4 = Clausen, 1924, J. Exp. Zool. 38: 423-36; 5 = Grell, 1969, DIS 44: 47; 6 = Mossige, 1951, DIS 25: 69; 7 = Stern, 1927, Biol. Zentralbl. 47: 361-69; 8 = Stern, 1934, DIS 1: 35. | Wing bends sharply upward in vicinity of anterior crossvein in extreme cases, with a small dark blot near vein L3 at level of deflection. Anterior crossveins may be reduced or absent. cytology: Placed in 34E2. Within Df(2L)b82a2 = Df(2L)34D2- 4;34E1-2 and Df(2L)fn7 = Df(2L)34E2-4;35B3-5, but not in Df(2L)b82a1 or Df(2L)el80f1 = Df(2L)34E2-4;35C3-5 (Ashburner). # J: Jammed location: 2-41.0. origin: Spontaneous. discoverer: Bridges, 23d3. phenotype: Wings often compressed into narrow strips, sometimes filled with fluid. Alula larger and square tipped with clumped bristles and bare regions. Alula modification is characteristicly least likely to overlap wild type. Com- pletely overlaps wild type at 19, almost never at 28 or 30. Not lethal when homozygous; viability, as in heterozygote, about 70% wild type. Classifiable in single dose triploids (Schultz, 1934, DIS 1: 55). RK1 at 28-30; RK2 at 25. alleles: J1 and J34e (Duncan); like J1 but produces more vigorous stock; RK1 at 28. Two X-ray-induced revertants Jrv99 and Jrv272 are not deficient for flanking markers; Jrv99 is associated with T(Y;2)Jrv99 (Salas and Lengyel, 1984, DIS 60: 243-44). cytology: Salivary chromosomes apparently normal (Bridges in Morgan, Bridges, and Schultz, 1937, Year Book - Carnegie Inst. Washington 36: 301). Placed in 31B-F on basis of region com- mon to deficiencies recovered as revertants of J (Sandler, 1977, Genetics 86: 567-82). Jag: Jagged Edith M. Wallace, unpublished. # Jag: Jagged location: 2-54.9 (0.1 unit from Bl). discoverer: L. V. Morgan, 34b20. phenotype: Jag/+ has end of wing cut off; better in early counts and above 25. Jag/Jag has reduced and roughened eyes and extremely jagged wings. RK2 as heterozygote; RK3 as homozygote. # Jammed: see J # jan: janus location: 3-99D (close to Sry|). synonym: Y. references: Yanicostas, Vincent, and Lepesant, 1989, Mol. Cell Biol. 9: 2526-35. phenotype: Two partially overlapping genes, janA and janB, regulate the expression of somatic sex differentiation. janA is expressed in a complex way in both males and females; janB is only expressed in males (Yanicostas et al., 1989). molecular biology: Genomic and cDNA clones were isolated and nucleotide and deduced amino acid sequences obtained. The genomic and cDNA sequences showed that both janA and janB con- tain a single long open reading frame. Both genes are tran- scribed in the same direction; the 5 end of the janB mRNA maps within the 3 untranslated region of the janA transcribed sequence, the overlapping region being 118 bases long. Some other attributes are listed in the following table: transcripts predicted protein gene size (kb) sex amino acids mol. wt. ______________________________________________________ janA 1.1 males 115 12 kd 0.95 males 0.8 males and females janB 0.84 males 140 15 kd The cDNA sequences of janA suggests the existence of alter- native transcript structures which have not been definitely determined yet. The size difference between the 0.8 kb and the 0.95 kb transcripts is the result of a difference in length of their poly(A) tails. The male-specific 0.95 kb janA transcript and the male-specific janB transcript are only expressed in germ line tissues, but the non-sex-specific 0.8 kb janA transcript is known to be expressed in both germ line and somatic tissues since detected in germ-line-less as well as normal adults. 37% of the amino acid residues of the two janus genes are identical at homologous positions and the last two 3 introns of both genes are located at identical posi- tions with respect to their protein-coding sequences, suggest- ing that janA and janB originated from a duplication of an ancestral transcription unit. # jaunty: see j # jaunty x: see jyx # javelin: see jv # javelinlike: see jvl #*je: jelly location: 3-46. origin: Spontaneous; arose simultaneously with mussed (3-50). discoverer: Mohr, 37l21. references: Mossige, 1939, DIS 12: 47. phenotype: Dark pinkish eye color. RK1. # Jon: Jonah A complex family of about 20 genes distributed at widely dispersed sites on the chromosomes of Drosophila melanogaster and expressed only in the midgut of larvae and adults. The function of the gene products are not known. The genes are found in small clusters at different chromosomal sites, as indicated in the following table. genes location cytology ( number of (single or genes at clustered) site _______________________________________________ Jon25B | 2-{13} 25B 3 Jon44E 2-{58} 44E 1 Jon65A | 3-{20} 65A 4 Jon66C | 3-{26} 66C 2 Jon99C1 / 3-{101} 99C 2 Jon99C2 | / 3-{101} 99C 3 Jon99F 3-{101} 99C 2 ( As indicated by in situ hybridization to the salivaries (Carlson and Hogness, 1985, Dev. Biol. 108: 341-54). A weak site at 67B was also identified by long exposure to the label but no genomic clones were identified (Wolfner, 1980, Ph.D thesis, Stanford University). Six gene clusters listed have repeats (direct, inverted, or both). | Described in detail at the end of text. / Allelic variants at 99C. Synonym: JonC ( and JonC |. origin: From cDNA clones from the poly(A)+ RNA of third instar larvae before the beginning of larvae metamorphosis. Sites identified by in situ hybridization with the reference cDNA probe. references: Akam and Carlson, 1985, EMBO J. 4: 155-61. Carlson and Hogness, 1985a, Dev. Biol. 108: 341-54. Carlson and Hogness, 1985b, Dev. Biol. 108: 355-68. phenotype: The Jon genes are expressed in various regions of the larval midgut (AMG, MMG, PMG) during all the larval stages (Akam and Carlson, 1985); expression disappears at pupation, but reappears in the adult midgut shortly after eclosion and remains throughout adult life. molecular biology: Genomic clones and subclones carrying Jonah genes from different chromosomal sites were constructed and isolated (Carlson and Hogness, 1985a, 1985b), revealing a fam- ily of imperfectly repeated genes. Jonah mRNA is abundant during all three larval instars and in the adult life, but different Jonah RNA's show spatial and temporal differences (Akam and Carlson, 1985; Carlson and Hogness, 1985a). The mature mRNA is about 910 bp in length and encodes a 28 kd translation product whose function has not been determined (Carlson and Hogness, 1985b). # Jon25B molecular biology: mRNA hybridizes strongly to larvae, weakly to adults (Carlson and Hogness, 1985b). # Jon65A molecular biology: Weak identity to other Jonah genes. mRNA hybridizes to both anterior and middle midgut of larvae (Akam and Carlson, 1985; Carlson and Hogness, 1985b). # Jon66C molecular biology: mRNA hybridizes to larvae only (Carlson and Hogness, 1985b). # Jon99C2 molecular biology: Shows considerable identity to many other Jonah genes. mRNA hybridizes strongly to anterior part of the posterior midgut of larvae (Akam and Carlson, 1985; Carlson and Hogness, 1985b). # jpl: see gfa # ju: jumper location: 3-91.09 (between se and e). origin: Wild population from Yugoslavia. references: Lenicek and Sesta, 1986, DIS 63: 163. phenotype: Flies have opened wings, oriented at an angle of 65 with respect to the longitudinal axis, and 10-30 with respect to the horizontal axis. Homozygotes show decreased flying ability and move from place to place by jumping. # Jutas: see Fs(3)Sz13 # jv: javelin location: 3-19.2 (0.9 unit to left of dv). discoverer: Mohr, 31j29. references: 1937, DIS 8: 12. Mohr and Mossige, 1943, Skrifter Norske Videnskaps-Akad. Oslo, I: Mat.-Naturv. Kl., No. 7. 51 pp. (fig.). phenotype: All bristles and hairs cylindrical, instead of tapered, with small enlargement before tip. Cell autonomous and useful as a marker for epidermal clones (Morata and Ripoll, 1975, Dev. Biol. 42: 211-21). RK2. alleles: jv1 and jv70b. cytology: Placed between 64C12 and 65E1 on the basis of its inclusion in Df(3L)Vn = Df(3L)64C12-D1;65D2-E1. # jvl: javelinlike location: 3-56.7. origin: Spontaneous. discoverer: Ives, 40l2. references: 1942, DIS 16: 48. phenotype: Resembles jv but bristles sometimes more crooked. Viability and productivity somewhat lower than normal. RK2. #*jyx: jaunty-x location: 1-24. origin: Spontaneous. discoverer: Bridges, 14i12. phenotype: Wings curved up at tips. Viability about 60% wild type. RK3.