#*Q: Queer wing location: 2- (not located). discoverer: E. M. Wallace, 1931. phenotype: Wings irregularly incised; marginal bristles irregu- lar. Heterozygote has low penetrance; homozygote better. RK3. # Qd: Quadroon location: 1-6.8. origin: Spontaneous. references: Thompson, 1959, DIS 33: 99. phenotype: Broad dark band on margins of all abdominal ter- gites, giving abdomen superficial appearance of uniform dark- ness. Viability of heterozygous female normal, of homozygous female < 10% normal, and of male 30% normal. Qd/Df(1)bi4 exhibit homozygous Qd phenotype as well as bi-like phenotype; Qd/bi and Qd/+ are normal with respect to bi (Banga, Bloom- quist, Brodberg, Pye, Larrivee, Mason, Boyd, and Pak, 1986, Chromosoma 93: 341-46). RK2. cytology: Placed in 4C5-6 based on its inclusion in Df(1)rb13 = Df(1)4C5-6;4D3-E1 and the localization of the X break in T(1;3)biD1 = T(1;3)4C5-6;65C3-5 (Banga et al., 1986). # qf: quetas-finas location: 3-60.7. origin: Spontaneous. references: Ribo, 1968, DIS 43: 59. phenotype: Macro- and microchaetae thinner and shorter; low fertility; viability good. # qs: quicksilver location: 1-39.5 (based on mapping of qs2. references: Craymer, 1984, DIS 60: 234-36. Wieschaus, Nusslein-Volhard, and Jurgens, 1984, Wilhelm Roux's Arch. Dev. Biol. 193: 296-307. Wright, 1987, Adv. Genet. 24: 127-222. Pentz, Black, and Wright, 1990, Biochem. Genet. 28: 151-71. phenotype: Recessive embryonic lethal; denticles and mouthparts unpigmented; cell viable in gynandromorphs causing depigmenta- tion of cuticle, including chaetae; viability reduced owing to weakened cuticle. Used as marker in the analysis of mosaic embryos (Gergen and Wieschaus, 1985, Dev. Biol. 109: 321-35). qs1, qs2, and qs3 hypomorphic in that expression varies with temperature and nutrition; some survival when reared on enriched medium; survivors smaller than normal and incom- pletely pigmented with a yellowish tinge; some extremely pale with bristles with very little pigmentation and with wings that when expanded are glassy clear and very fragile. The extremely pale qs2/Y never exhibit melanotic wound reaction, and puparia underpigmented. qs embryos derived from homozy- gous germ-line clones do not hatch and exhibit head defects and abnormalities of germ-band shortening; heterozygous embryos from such clones exhibit 75% survival; homozygous clones behave as meiotic mutant yielding 8% patroclinous males (Wieschaus and Noel, 1986, Wilhelm Roux's Arch. Dev. Biol. 195: 63-73). Phenol oxidase activity of any surviving qs flies significantly depressed, in some cases being undetect- able; all three components, A1, A2, and A3, coordinately reduced; activator activity normal. Phenol oxidase deficiency leads to significant accumulations of catecholamine pools in qs2 males 60 to 80 min after eclosion: three-to-eight-fold increases in N-|-alanyldopamine and N-acetyldopamine and two- fold increases in dopamine (Pentz, Black, and Wright). alleles: allele origin discoverer synonym ref ( comments __________________________________________________________________________ qs1 ENU Crosby, 1982 1, 4 lethal qs2 EMS Sherald su18 2, 4 recovered as suppressor of b; cold sensitive in males and females | qs3 EMS ftdN1 3, 4 embryonic lethal qs4 EMS ftdN9 3 embryonic lethal qs5 EMS ftd 3 embryonic lethal qs6 EMS ftd 3 embryonic lethal qs7 EMS ftd 3 embryonic lethal qs8 EMS ftd 3 embryonic lethal qs9 EMS ftd 3 embryonic lethal ( 1 = Craymer, 1984, DIS 60: 234-36; 2 = Sherald, 1981, Mol. Gen. Genet. 183: 102-06; 3 = Wieschaus, Nusslein-Volhard, and Jurgens, 1984, Wilhelm Roux's Arch. Dev. Biol. 193: 296-307; 4 = Wright, 1987, Adv. Genet. 24: 127-222. | At 25, qs2/qs2 females only 1% viable but qs2/Y males as viable as wild type (Pentz et al., 1990). cytology: Placed in 10F1-10 based on its inclusion in Df(1)RA47 = Df(1)10F1;10F10 (Wieschaus et al., 1984). # qua: quail (T. Schupbach) location: 2-53. origin: Induced by ethyl methanesulfonate. discoverer: Wieschaus and Nusslein-Volhard. references: Steward and Nusslein-Volhard, 1986, Genetics 113: 665-78. phenotype: Female sterile; nurse-cell contents not transported into the egg; follicle cells produce normal chorion around tiny eggs, which remain unfertilized. alleles: qua1 isolated as WP by Wieschaus and Nsslein-Volhard; f2qua2-qua7 by Steward; qua8-qua12 by Schupbach and Wieschaus as HK, HM, PX, QE, and QT. cytology: Placed in 36C2-C4 by Steward and Nusslein-Volhard; uncovered by Df(2L)TW137 = Df(2L)36C2-4;37B9-C1, but not by Df(2L)VA18 = Df(2L)36C4-D1;37C2-D1. # Quadroon: see Qd # quail: see qua # Queer wing: see Q # quetas finas: see qf # qui: quit (T. Schupbach) location: 2-105. origin: Induced by ethyl methanesulfonate. references: Schupbach and Wieschaus. phenotype: Female sterile; ovaries of homozygous females con- tain egg chambers with normal and abnormal numbers of nurse cells, which start degenerating at early stages of oogenesis. alleles: Two: quiQL = qui1 and quiPX. cytology: Localized to 59D8-60A7, since qui-1 and qui-2 recovered as QL and PX, respectively, uncovered by Df(2R)bw- S46 = Df(2R)59D8-11;60A7. # quicksilver: see qs # quit: see qui